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- Table of Contents
Facts about Sorting nexin-10.
Required for its localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and so bone resorption.
Human | |
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Gene Name: | SNX10 |
Uniprot: | Q9Y5X0 |
Entrez: | 29887 |
Belongs to: |
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sorting nexin family |
MGC33054; sorting nexin 10; sorting nexin-10
Mass (kDA):
23.598 kDA
Human | |
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Location: | 7p15.2 |
Sequence: | 7; NC_000007.14 (26291862..26374383) |
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. May also localize to nucleus and endoplasmic reticulum.
PMID: 11485546 by Teasdale R.D., et al. A large family of endosome-localized proteins related to sorting nexin 1.
PMID: 17012226 by Qin B., et al. Sorting nexin 10 induces giant vacuoles in mammalian cells.