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- Table of Contents
Facts about Small nuclear ribonucleoprotein-associated proteins B and B'.
Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it's involved in histone pre-mRNA 3'-end processing (PubMed:12975319).
Human | |
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Gene Name: | SNRPB |
Uniprot: | P14678 |
Entrez: | 6628 |
Belongs to: |
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snRNP SmB/SmN family |
CODB polypeptide of Sm protein; Sm protein B/B'; small nuclear ribonucleoprotein polypeptides B and B'; small nuclear ribonucleoprotein polypeptides B and B1; small nuclear ribonucleoprotein-associated proteins B and B'; SmB/B'; Sm-B/B'sm-B/Sm-B'; SmB/SmB'; snRNP-Bsmall nuclear ribonucleoprotein polypeptide B; SNRPB1
Mass (kDA):
24.61 kDA
Human | |
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Location: | 20p13 |
Sequence: | 20; NC_000020.11 (2461642..2470789, complement) |
Cytoplasm, cytosol. Nucleus. SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
PMID: 2531083 by van Dam A., et al. Cloned human snRNP proteins B and B' differ only in their carboxy- terminal part.
PMID: 2522186 by Schmauss C., et al. A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'.