This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Synphilin-1.
Isoform 2 modulates SNCA monoubiquitination by SIAH1. .
Human | |
---|---|
Gene Name: | SNCAIP |
Uniprot: | Q9Y6H5 |
Entrez: | 9627 |
Belongs to: |
---|
No superfamily |
Alpha-synuclein-interacting protein; MGC39814; Sph1; synphilin-1; synuclein, alpha interacting protein; SYPH1
Mass (kDA):
100.409 kDA
Human | |
---|---|
Location: | 5q23.2 |
Sequence: | 5; NC_000005.10 (122311354..122464219) |
Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta.
Cytoplasm. Detected in cytoplasmic inclusion bodies, together with SNCA.
PMID: 10319874 by Engelender S., et al. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.
PMID: 10967135 by Engelender S., et al. Organization of the human synphilin-1 gene, a candidate for Parkinson's disease.