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- Table of Contents
Facts about SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1.
During neural development a switch from a stem/progenitor into a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult condition. The transition from proliferating neural stem/progenitor cells into postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.
Human | |
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Gene Name: | SMARCD1 |
Uniprot: | Q96GM5 |
Entrez: | 6602 |
Belongs to: |
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SMARCD family |
BAF60Amammalian chromatin remodeling complex BRG1-associated factor 60A; BRG1-associated factor 60A; chromatin remodeling complex BAF60A subunit; CRACD1; Rsc6p; subfamily d, member 1; SWI/SNF complex 60 kDa subunit A; SWI/SNF complex 60 kDa subunit; SWI/SNF related, matrix associated, actin dependent regulator of chromatin; SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily D member 1,60 kDa BRG-1/Brm-associated factor subunit A; Swp73-like protein
Mass (kDA):
58.233 kDA
Human | |
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Location: | 12q13.12 |
Sequence: | 12; NC_000012.12 (50085236..50100707) |
Expressed in all tissues tested, including brain, heart, kidney, liver, lung, muscle, pancreas and placenta.
Nucleus.
PMID: 8804307 by Wang W., et al. Diversity and specialization of mammalian SWI/SNF complexes.
PMID: 8895581 by Wang W., et al. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.