Sarcolipin Antibodies

AND SLN ELISA kits, Sarcolipin Proteins

Many biological assays use antibodies to detect Sarcolipin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sarcolipin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sarcolipin antibodies...

We validate the specificity of these antibodies to Sarcolipin by testing them on tissues known to express SLN positively and negatively. Browse below to find the SLN antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLN Infographic by Boster Bio

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SLN (NM_003063) Human Over-expression Lysate

Human

$628
Cat # LS006588
100 µg

SLN Overview

Facts about Sarcolipin.

SLN 3D structure. Source: alphafold

Sarcolipin (SLN)

Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle.

Required for muscle-based, non-shivering thermogenesis (By similarity). .

Gene Information

Human
Gene Name:	SLN
Uniprot:	O00631
Entrez:	6588

Family

Belongs to:

sarcolipin family

Alternative Names

Sarcolipin

Molecular Weight

Mass (kDA):
3.762 kDA

Genomic Context


Human

Location:	11q22.3
Sequence:	11; NC_000011.10 (107707378..107712056, complement)

Subcellular Localizations

Sarcoplasmic reticulum membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

Interacting Proteins

CCDC155
SYNE4
TMEM79

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLN

References

PMID: 9367679 by Odermatt A., et al. Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease.

PMID: 9575189 by Odermatt A., et al. Sarcolipin regulates the activity of SERCA1, the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase.