SLCO2B1 Antibodies

AND SLCO2B1 ELISA kits, SLCO2B1 Proteins

Many biological assays use antibodies to detect SLCO2B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLCO2B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLCO2B1 antibodies...

We validate the specificity of these antibodies to SLCO2B1 by testing them on tissues known to express SLCO2B1 positively and negatively. Browse below to find the SLCO2B1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLCO2B1 Infographic by Boster Bio

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SLCO2B1 Overview

Facts about Solute carrier organic anion transporter family member 2B1.

SLCO2B1 3D structure. Source: alphafold

Solute carrier organic anion transporter family member 2B1 (SLCO2B1)

Mediates the Na(+)-independent transport of organic anions like taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. .

Gene Information

Human
Gene Name:	SLCO2B1
Uniprot:	O94956
Entrez:	11309

Family

Belongs to:

organo anion transporter (TC 2.A.60) family

Alternative Names

OATP2B1OATP-RP2; OATPBDKFZp686E0517; OATP-BKIAA0880; OATPRP2; Organic anion transporter B; Organic anion transporter polypeptide-related protein 2; SLC21A9solute carrier organic anion transporter family member 2B1; solute carrier family 21 (organic anion transporter), member 9; Solute carrier family 21 member 9; solute carrier organic anion transporter family, member 2B1

Molecular Weight

Mass (kDA):
76.711 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (75151107..75206549)

Tissue Specificity

Isoform 1 has it's highest expression in brain, it is the major form expressed in duodenum, kidney, placenta, and skeletal muscle. Isoform 3 predominates in liver.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Food-drug Interactions
Asthma
Mammary Neoplasms
Steroid Sulfatase Deficiency Disease
Malignant Neoplasm Of Prostate
Hiv Infections
Neoplasm Metastasis
Carcinoma
Immunologic Deficiency Syndromes

Myopathy
Neoplasms, Hormone-dependent
Malignant Paraganglionic Neoplasm
Hypercholesterolemia
Prostatic Neoplasms
Cholangiocarcinoma
Dyslipidemias

Pathways

Transport
Intestinal Absorption
Localization
Excretion
Drug Transport
Osteoblast Differentiation
Cell Proliferation
Response To Statin
Secretion
Osteoclast Differentiation
Aging
Proteolysis
Platelet Activation

Sulfate Transport
Platelet Aggregation
Transepithelial Transport
Reverse Transcription
Lipid Homeostasis
Transmembrane Transport
Glycosylation

PTMs

Carboxylation
Biotinylation

Phosphorylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLCO2B1

References

PMID: 10873595 by Tamai I., et al. Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

PMID: 16754786 by Hanggi E., et al. Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1.