SLC7A11 Antibodies

AND SLC7A11 ELISA kits, SLC7A11 Proteins

Many biological assays use antibodies to detect SLC7A11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC7A11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC7A11 antibodies...

We validate the specificity of these antibodies to SLC7A11 by testing them on tissues known to express SLC7A11 positively and negatively. Browse below to find the SLC7A11 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC7A11 Infographic by Boster Bio

All SLC7A11 Products

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Specificity

Applications

Price

Anti-xCT Rabbit Monoclonal Antibody

8 Q&As

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M03036
100 μl

SLC7A11 Overview

Facts about Cystine/glutamate transporter.

SLC7A11 3D structure. Source: alphafold

Cystine/glutamate transporter (SLC7A11)

Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. .

Gene Information

Human
Gene Name:	SLC7A11
Uniprot:	Q9UPY5
Entrez:	23657

Family

Belongs to:

amino acid-polyamine-organocation (APC) superfamily

Alternative Names

Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; CCBR1; cystine/glutamate transporter; Member 11 (Slc7a11); SLC7A11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT; xCTCCBR1

Molecular Weight

Mass (kDA):
55.423 kDA

Genomic Context


Human

Location:	4q28.3
Sequence:	4; NC_000004.12 (138164097..138242349, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Glioma
Brain Neoplasms
Nerve Degeneration
Neurodegenerative Disorders
Nervousness
Neurotoxicity Syndromes
Hyperplasia
Sarcoma
Parkinson Disease
Malignant Neoplasm Of Breast

Inflammation
Kaposi Sarcoma
Hypoxia
Lymphoma
Malignant Paraganglionic Neoplasm
Alzheimer's Disease
Hiv Infections

Interacting Proteins

CD44

Pathways

Transport
Cell Death
Amino Acid Transport
Cell Proliferation
Pathogenesis
Secretion
Cell Cycle
Neuroprotection
Cell Growth
Cell Cycle Arrest
Localization
Glutamate Homeostasis
Cellular Homeostasis

Pigmentation
Drug Resistance
Glutamate Secretion
Cell Migration
Ossification
Cell Differentiation
Long-term Memory

PTMs

Phosphorylation
Reduction

Biotinylation
Cleavage

Research Areas

Amino Acids, Drugs and other small molecules
Cell Biology
Lipid and Metabolism
Neuronal Cell Markers
Neuroscience

Neurotransmission
Plasma Membrane Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC7A11

References

PMID: 11213471 by Sato H., et al. Molecular cloning and expression of human xCT, the light chain of amino acid transport system xc-.

PMID: 11133847 by Bridges C.C., et al. Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells.