SLC6A9 Antibodies

AND SLC6A9 ELISA kits, SLC6A9 Proteins

Many biological assays use antibodies to detect SLC6A9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC6A9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC6A9 antibodies...

We validate the specificity of these antibodies to SLC6A9 by testing them on tissues known to express SLC6A9 positively and negatively. Browse below to find the SLC6A9 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC6A9 Infographic by Boster Bio

All SLC6A9 Products

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Applications

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Glyt1 (SLC6A9) (NM_006934) Human Over-expression Lysate

Human

$960
Cat # LS006536
100 µg

SLC6A9 Overview

Facts about Sodium- and chloride-dependent glycine transporter 1.

SLC6A9 3D structure. Source: alphafold

Sodium- and chloride-dependent glycine transporter 1 (SLC6A9)

Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.

Gene Information

Human
Gene Name:	SLC6A9
Uniprot:	P48067
Entrez:	6536

Family

Belongs to:

sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Alternative Names

DKFZp547A1118; GlyT1; GlyT-1; GLYT1glyT-1; SLC6A9; sodium- and chloride-dependent glycine transporter 1; solute carrier family 6 (neurotransmitter transporter, glycine), member 9; Solute carrier family 6 member 9

Molecular Weight

Mass (kDA):
78.26 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (43996483..44031462, complement)

Tissue Specificity

Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Schizophrenia
Nervousness
Psychotic Disorders
Malnutrition
Impairment (finding)
Pcp - Hallucinogen-related Disorder
Cognition Disorders
Choriocarcinoma
Pain
Depressive Disorder
Placental Choriocarcinoma
Mental Disorders

Neurobehavioral Manifestations
Psychoses, Substance-induced
Anxiety Disorders
Colitis
Encephalopathies
Intestinal Diseases
Psychomotor Disorders

Pathways

Transport
Glycine Transport
Localization
Prepulse Inhibition
Synaptic Transmission
Exocytosis
Pathogenesis
Reflex
Swimming
Cognition
Associative Learning
Endocytosis
Ovulation

Startle Response
Cellular Localization
Long-term Synaptic Potentiation
Habituation
Aging
Brain Development
Fertilization

PTMs

Phosphorylation
Reduction
Glycosylation

Cleavage
Acetylation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC6A9

References

PMID: 8183239 by Kim K.-M., et al. Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.

PMID: 27773429 by Kurolap A., et al. Loss of Glycine Transporter 1 Causes a Subtype of Glycine Encephalopathy with Arthrogryposis and Mildly Elevated Cerebrospinal Fluid Glycine.