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SLC6A12 Antibodies

AND SLC6A12 ELISA kits, SLC6A12 Proteins

Many biological assays use antibodies to detect SLC6A12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC6A12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC6A12 antibodies...

We validate the specificity of these antibodies to SLC6A12 by testing them on tissues known to express SLC6A12 positively and negatively. Browse below to find the SLC6A12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC6A12 Infographic by Boster Bio

SLC6A12 protein infographic

All SLC6A12 Products

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Product

Figures

Specificity

Applications

Price

Anti-S6A12 SLC6A12 Antibody

Human

ELISA, WB

$380
Cat # A07083
100ul

SLC6A12 (NM_003044) Human Over-expression Lysate

Human

$960
Cat # LS006539
100 µg

SLC6A12 Overview

Facts about Sodium- and chloride-dependent betaine transporter.

SLC6A12 3D structure

SLC6A12 3D structure. Source: alphafold

Sodium- and chloride-dependent betaine transporter (SLC6A12)

Transports betaine and GABA.
May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.

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Gene Information

Human
Gene Name:	SLC6A12
Uniprot:	P48065
Entrez:	6539

Gene Information

Family

Belongs to:

sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Family

Alternative Names

BGT1; FLJ38727; gamma-aminobutyric acid transporter; solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

Molecular Weight

Mass (kDA):
69.368 kDA

Molecular Weight

Genomic Context


Human

Location:	12p13.33
Sequence:	12; NC_000012.12 (190081..214157, complement)

Tissue Specificity

Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Partial Seizure
Nervousness
Disease Of Adrenal Medulla
Kindling, Neurologic
Epilepsy
Epilepsies, Partial
Cholangiocarcinoma
Uterine Cervical Neoplasm
Ataxia
Epilepsy, Generalized
Malignant Tumor Of Cervix
Carcinoma

Memory Disorders
Edema
Epilepsy, Reflex
Malignant Neoplasms
Neoplasms
Cervical Intraepithelial Neoplasia
Asthma

Disease

Interacting Proteins

REL
SCRIB

Interacting Proteins

Pathways

Transport
Cellular Localization
Gamma-aminobutyric Acid Transport
Neurotransmitter Transport
Localization
Reflex

Pathways

PTMs

Biotinylation

Methylation

Research Areas

Neuroscience

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC6A12

References

PMID: 7589472 by Rasola A., et al. Molecular cloning and functional characterization of a GABA/betaine transporter from human kidney.

PMID: 7861179 by Borden L.A., et al. Cloning and expression of a betaine/GABA transporter from human brain.