SLC40A1 Antibodies

AND SLC40A1 ELISA kits, SLC40A1 Proteins

Many biological assays use antibodies to detect SLC40A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC40A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC40A1 antibodies...

We validate the specificity of these antibodies to SLC40A1 by testing them on tissues known to express SLC40A1 positively and negatively. Browse below to find the SLC40A1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC40A1 Infographic by Boster Bio

All SLC40A1 Products

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Anti-SLC40A1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A01953-2
100 μg/vial

SLC40A1 Overview

Facts about Solute carrier family 40 member 1.

SLC40A1 3D structure. Source: alphafold

Solute carrier family 40 member 1 (SLC40A1)

May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

Gene Information

Human
Gene Name:	SLC40A1
Uniprot:	Q9NP59
Entrez:	30061

Family

Belongs to:

ferroportin (FP) (TC 2.A.100) family

Alternative Names

Ferroportin; Ferroportin-1; FPN1; FPN1IREG1ferroportin 1; HFE4; HFE4ferroportin-1; IREG1; Iron-regulated transporter 1; member 3; MST079; MTP1; putative ferroportin 1 variant IIIB; SLC11A3; SLC11A3iron regulated gene 1; SLC40A1; solute carrier family 11 (proton-coupled divalent metal ion transporters); solute carrier family 40 (iron-regulated transporter), member 1; solute carrier family 40 member 1

Molecular Weight

Mass (kDA):
62.542 kDA

Genomic Context


Human

Location:	2q32.2
Sequence:	2; NC_000002.12 (189560590..189580811, complement)

Tissue Specificity

Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Localized to the basolateral membrane of polarized epithelial cells.

Diseases

Hemochromatosis
Iron Overload
Hereditary Hemochromatosis
Anemia
Liver Cirrhosis
Diabetes Mellitus
Juvenile Hemochromatosis
Iron Metabolism Disorders
Hereditary Diseases
Cardiomyopathies
Malignant Neoplasms
Hepatitis
Tuberculosis

Neoplasms
Haploinsufficiency
Arthritis
Iron Deficiency
Liver Diseases
Malignant Neoplasm Of Breast
Fibrosis

Interacting Proteins

Pathways

Transport
Localization
Pathogenesis
Pigmentation
Inflammatory Response
Endoderm Formation
Cytolysis
Gastrulation
Intestinal Absorption
Ureteric Bud Formation
Reverse Transcription

Cytokine Production
Muscle Hypertrophy
Excretion
Secretion
Kidney Development

PTMs

Cleavage

Research Areas

Cancer
Lipid and Metabolism
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC40A1

References

PMID: 10747949 by Abboud S., et al. A novel mammalian iron-regulated protein involved in intracellular iron metabolism.

PMID: 10882071 by McKie A.T., et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.