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- Table of Contents
Facts about Solute carrier family 2, facilitated glucose transporter member 8.
Seems like a dual-specific sugar transporter because it is inhibitable by fructose (By similarity). .
Human | |
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Gene Name: | SLC2A8 |
Uniprot: | Q9NY64 |
Entrez: | 29988 |
Belongs to: |
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major facilitator superfamily |
GLUT-8; GLUT8solute carrier family 2 (facilitated glucose transporter) member 8; GLUTX1facilitated glucose transporter member 8; solute carrier family 2 (facilitated glucose transporter), member 8
Mass (kDA):
50.819 kDA
Human | |
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Location: | 9q33.3 |
Sequence: | 9; NC_000009.12 (127397138..127407898) |
Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.
PMID: 10821868 by Doege H., et al. GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity.
PMID: 10671487 by Ibberson M.R., et al. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues.