Pendrin Antibodies

Pendrin (SLC26A4)

Sodium-independent transporter of chloride and iodide. .

Gene Information

Human
Gene Name:	SLC26A4
Uniprot:	O43511
Entrez:	5172

Family

Belongs to:
SLC26A/SulP transporter (TC 2.A.53) family

Alternative Names

DFNB4; EVA; PDSTDH2B; pendrin; Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4; solute carrier family 26, member 4

Molecular Weight

Mass (kDA):
85.723 kDA

Genomic Context

Human
Location:	7q22.3
Sequence:	7; NC_000007.14 (107660828..107717809)

Tissue Specificity

High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Localizes to the apical brush border of cells in the cortical collecting ducts of the kidney.

Diseases

• Complete Hearing Loss
• Pendred's Syndrome
• Sensorineural Hearing Loss (disorder)
• Goiter
• Hypothyroidism
• Deafness Congenital
• Nodular Goiter
• Dysplasia
• Thyroid Neoplasm
• Adenoma
• Carcinoma
• Neoplasms

• Malignant Neoplasms
• Thyroid Diseases
• Hypertensive Disease
• Congenital Ear Anomaly Nos (disorder)
• Acidosis
• Alkalosis
• Hereditary Diseases

Pathways

• Transport
• Secretion
• Localization
• Pathogenesis
• Excretion
• Iodide Transport
• Sulfate Transport
• Ion Transport
• Anion Transport
• Ear Development
• Inner Ear Development
• Chloride Transport
• Glycosylation

• Methylation
• Regulation Of Blood Pressure
• Cell Proliferation
• Acid Secretion
• Translation
• Fluid Transport
• Cell Growth

PTMs

• Methylation
• Phosphorylation
• Iodination
• Glycosylation

• Nitration
• Biotinylation
• Reduction
• Deacetylation

• Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC26A4

Boster Bio - Best Uses Of The SLC26A4 Marker

If you're looking for high-affinity antibodies for the protein SLC26A4, consider Boster Bio. Boster produces antibodies that have been validated on various platforms, using known positive and negative samples for high specificity and affinity. Boster also rewards first reviewers with credits for their products, and they're available globally. Learn more about their history and their products. We'll also explore the ways that their antibodies can help your research.

Boster Bio Anti-SLC26A4 Marker

Boster Bio Anti-SLC26A4, Catalog number A00919-1 is an antigen against human SLC26A4. It reacts with the recombinant Human or Mouse proteins. This antibody can also be used to perform Western Blotting. This is a lyophilized product that contains a 100 ug/vial charging. It has been thoroughly tested for use in WB, IHC, and Flow.

The Boster Bio Anti-SLC26A4, monoclonal antibody reacts with Human and is non-hazardous. It is made in 10mM PBS and 0.05 percent BSA. It is comprised of a synthetic peptide , derived from the human DOG-1 protein and a carrier protein. It is highly specific for SLC26A4/Bcl2 as well as aids in the identification of these proteins in your body.

Boster provides high-affinity primary antibodies

Primary antibodies are immunoglobulins that are able to bind to specific antigens. Their affinity and specificity are usually the most important factors in determining their quality. The first measures the strength of an antigen-antibody binding, while the latter refers to the extent of unintended binding. High-affinity antibodies are useful in the purification, detection and measuring specific antigens.

The primary antibody is used for multiple applications, including immunohistochemistry, Western blotting, immunohistochemistry, histopathology, and protein assays. Secondary antibodies are employed in flow cytometry and ELISA tests. Both types of tests determine the presence or absence specific cell types. They can be used to identify the protein composition and determine the functions of certain organelles.

The history of Steven Boster

Steven Boster, a Staunton-based retired executive, died June 6 2022, at the age of seventy-one. Born in Joliet, IL, he was the son of Donald Sr. and Evelyn Meier. A former U.S. Army veteran, He was also a part-time member of Concordia Hall. Steve is survived by his wife Nina and his two daughters Natosha , and Crystal Peck, six grandchildren 4 Brothers and two sisters, Kimberly Blanton, Tammy Boster and Tammy Boster. He is also survived by his son Jonathan and his grandson Cory and his family, who reside in Herrin, IL.

Steve loved family and friends more than anything else. He was proud of his children and loved them more than anything else. Steve was the first to arrive on the scene when his car exploded at 2 a.m. His generosity extended to his family and friends, whom were treated like family. In his spare time, he would sing to his friends. He loved a particular gospel song.