SLC25A15 Antibodies

AND SLC25A15 ELISA kits, SLC25A15 Proteins

Many biological assays use antibodies to detect SLC25A15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC25A15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC25A15 antibodies...

We validate the specificity of these antibodies to SLC25A15 by testing them on tissues known to express SLC25A15 positively and negatively. Browse below to find the SLC25A15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC25A15 Infographic by Boster Bio

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SLC25A15 Overview

Facts about Mitochondrial ornithine transporter 1.

SLC25A15 3D structure. Source: alphafold

Mitochondrial ornithine transporter 1 (SLC25A15)

Ornithine-citrulline antiporter. Connects the cytosolic and the intramitochondrial reactions of the urea cycle by exchanging cytosolic ornithine with matrix citrulline (PubMed:12807890).

The stoichiometry is close to 1:1 (By similarity). .

Gene Information

Human
Gene Name:	SLC25A15
Uniprot:	Q9Y619
Entrez:	10166

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

D13S327; mitochondrial ornithine transporter 1; ORC1; ornithine transporter 1; ORNT1HHH; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member15; Solute carrier family 25 member 15

Molecular Weight

Mass (kDA):
32.736 kDA

Genomic Context


Human

Location:	13q14.11
Sequence:	13; NC_000013.11 (40789611..40812460)

Tissue Specificity

Highly expressed in liver, pancreas, testis, lung and small intestine. Lower levels are detected in spleen, kidney, brain and heart.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Hyperammonemia
Hyperornithinemia-hyperammonemia-homocitrullinuria Syndrome
Inborn Errors Of Metabolism
Hyperornithinemia
Metabolic Diseases
Encephalopathies
Hypertransaminasaemia
Mitochondrial Diseases
Paraplegia
Ornithine Carbamoyltransferase Deficiency
Liver Dysfunction
Muscle Spasticity

Blood Coagulation Disorders
Citrullinemia
Gait Abnormality
Encephalopathy Acute
Moderate Mental Retardation
Polyneuropathy

Pathways

Urea Cycle
Transport
Ornithine Transport
Antiport
Pathogenesis
Excretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A15

References

PMID: 10369256 by Camacho J.A., et al. Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter.

PMID: 12807890 by Fiermonte G., et al. The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.