SLC22A5 Antibodies

AND SLC22A5 ELISA kits, SLC22A5 Proteins

Many biological assays use antibodies to detect SLC22A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC22A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC22A5 antibodies...

We validate the specificity of these antibodies to SLC22A5 by testing them on tissues known to express SLC22A5 positively and negatively. Browse below to find the SLC22A5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC22A5 Infographic by Boster Bio

All SLC22A5 Products

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Product

Figures

Specificity

Applications

Price

Anti-Solute carrier family 22 member 5/SLC22A5 Antibody Picoband®

8 Q&As

Mouse, Rat

$370
Cat # PA2174
100 μg/vial

Anti-SLC22A5 Antibody

Human, Mouse, Rat

$405
Cat # A01527
100ul

Solute carrier family 22 member 5 (SLC22A5) (NM_003060) Human Over-expression Lysate

Human

$628
Cat # LS006584
100 µg

SLC22A5 Overview

Facts about Solute carrier family 22 member 5.

SLC22A5 3D structure. Source: alphafold

Solute carrier family 22 member 5 (SLC22A5)

Sodium-ion dependent, higher affinity carnitine transporter. Involved from the active cellular uptake of carnitine.

Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium.

Gene Information

Human
Gene Name:	SLC22A5
Uniprot:	O76082
Entrez:	6584

Family

Belongs to:

major facilitator (TC 2.A.1) superfamily

Alternative Names

CDSP; FLJ46769; High-affinity sodium-dependent carnitine cotransporter; OCTN2; OCTN2high-affinity sodium dependent carnitine cotransporter; OCTN2VT; organic cation transporter 2; organic cation transporter 5; Organic cation/carnitine transporter 2; SCD; SLC22A5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; solute carrier family 22 member 5

Molecular Weight

Mass (kDA):
62.752 kDA

Genomic Context


Human

Location:	5q31.1
Sequence:	5; NC_000005.10 (132369704..132395614)

Tissue Specificity

Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Crohn Disease
Renal Carnitine Transport Defect
Inflammatory Bowel Diseases
Intestinal Diseases
Cardiomyopathies
Colitis
Ulcerative Colitis
Ulcer
Myopathy
Hypoglycemia
Steatosis
Steatohepatitis

Inflammation
Dysequilibrium Syndrome
Arthritis
Hyperammonemia
Rheumatoid Arthritis
Hypertrophy
Malignant Neoplasms

Pathways

Transport
Carnitine Transport
Fatty Acid Oxidation
Localization
Excretion
Pathogenesis
Cation Transport
Secretion
Organic Cation Transport
Intestinal Absorption
Immune Response
Fatty Acid Beta-oxidation
Lipid Storage

Lactation
Antiport
Urea Cycle
Transmembrane Transport
Cell Proliferation
Cellular Localization
Aging

PTMs

Oxidation
Methylation
Biotinylation
Phosphorylation
Hydroxylation

Glycosylation
Reduction
Citrullination
Dephosphorylation
Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC22A5

References

PMID: 9618255 by Wu X., et al. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.

PMID: 9685390 by Tamai I., et al. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2.