SLC1A5 Antibodies

AND SLC1A5 ELISA kits, SLC1A5 Proteins

Many biological assays use antibodies to detect SLC1A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC1A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC1A5 antibodies...

We validate the specificity of these antibodies to SLC1A5 by testing them on tissues known to express SLC1A5 positively and negatively. Browse below to find the SLC1A5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC1A5 Infographic by Boster Bio

All SLC1A5 Products

Product

Figures

Specificity

Applications

Price

Anti-SLC1A5 Antibody

Human, Mouse, Rat

$405
Cat # A01474
100ul

SLC1A5 (NM_005628) Human Over-expression Lysate

Human

$628
Cat # LS006510
100 µg

SLC1A5 Overview

Facts about Neutral amino acid transporter B(0).

SLC1A5 3D structure. Source: alphafold

Neutral amino acid transporter B(0) (SLC1A5)

Sodium-dependent amino acids transporter which has a wide substrate specificity, with a taste for zwitterionic amino acids. It accepts as substrates all neutral amino acids, such as glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519, PubMed:29872227).

Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous mix of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). .

Gene Information

Human
Gene Name:	SLC1A5
Uniprot:	Q15758
Entrez:	6510

Family

Belongs to:

dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family

Alternative Names

AAAT; ASCT2M7VS1; ATB(0); Baboon M7 virus receptor; M7V1ATBO; neutral amino acid transporter B; neutral amino acid transporter B(0); R16; RD114 virus receptor; RD114/simian type D retrovirus receptor; RDR; RDRCFLJ31068; Sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 (neutral amino acid transporter), member 5; Solute carrier family 1 member 5

Molecular Weight

Mass (kDA):
56.598 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (46774883..46788594, complement)

Tissue Specificity

Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Diseases

Malignant Neoplasms
Neoplasms
Liver Carcinoma
Hypoxia
Liver Neoplasms
Glioma
Pre-eclampsia
Choriocarcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Ischemia
Malignant Paraganglionic Neoplasm
Schizophrenia

Uterine Neoplasms
Neoplasm Metastasis
Adenocarcinoma
Acidosis
Reticuloendothelial Hyperplasia
Prostatic Neoplasms
Reticuloendotheliosis, Avian

Interacting Proteins

RNF5

Pathways

Transport
Amino Acid Transport
Glutamine Transport
Localization
Cell Growth
Neutral Amino Acid Transport
Pathogenesis
Syncytium Formation
D-serine Transport
Glycine Transport
Glycosylation
Cell Death
Autophagy

Serine Transport
Cell Migration
Leucine Transport
Reverse Transcription
Translation
Protein N-linked Glycosylation
Mrna Transcription

PTMs

Phosphorylation
Glycosylation

Carboxylation
Cleavage

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC1A5

References

PMID: 8702519 by Kekuda R., et al. Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line.

PMID: 10051606 by Rasko J.E.J., et al. The RD114/simian type D retrovirus receptor is a neutral amino acid transporter.