Thiamine transporter 1 Antibodies

AND SLC19A2 ELISA kits, Thiamine transporter 1 Proteins

Many biological assays use antibodies to detect Thiamine transporter 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thiamine transporter 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thiamine transporter 1 antibodies...

We validate the specificity of these antibodies to Thiamine transporter 1 by testing them on tissues known to express SLC19A2 positively and negatively. Browse below to find the SLC19A2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC19A2 Infographic by Boster Bio

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SLC19A2 (NM_006996) Human Over-expression Lysate

Human

$960
Cat # LS010560
100 µg

SLC19A2 Overview

Facts about Thiamine transporter 1.

SLC19A2 3D structure. Source: alphafold

Thiamine transporter 1 (SLC19A2)

High-affinity transporter for the intake of thiamine. .

Gene Information

Human
Gene Name:	SLC19A2
Uniprot:	O60779
Entrez:	10560

Family

Belongs to:

reduced folate carrier (RFC) transporter (TC 2.A.48) family

Alternative Names

high affinity thiamine transporter; reduced folate carrier protein (RFC) like; solute carrier family 19 (thiamine transporter), member 2; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; thiamine transporter 1; THT1; ThTr1; ThTr-1; THTR1thTr-1; TRMA

Molecular Weight

Mass (kDA):
55.4 kDA

Genomic Context


Human

Location:	1q24.2
Sequence:	1; NC_000001.11 (169463909..169485970, complement)

Tissue Specificity

Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Anemia
Anemia, Megaloblastic
Diabetes Mellitus
Thiamine-responsive Megaloblastic Anemia
Leukemia
Complete Hearing Loss
Sensorineural Hearing Loss (disorder)
5,10-methylenetetrahydrofolate Reductase Deficiency
Malignant Neoplasms
Leukemia L1210
Neoplasms
Megaloblastic Anemia, Thiamine-responsive, With Diabetes Mellitus And Sensorineural Deafness
Thiamine Deficiency

Acute Lymphocytic Leukemia
Malignant Neoplasm Of Breast
Down Syndrome
Mammary Neoplasms
Congenital Abnormality
Complications Of Diabetes Mellitus
Acute Erythroblastic Leukemia

Pathways

Transport
Thiamine Transport
Methotrexate Transport
Localization
Pathogenesis
Intestinal Absorption
Translation
Glycosylation
Drug Resistance
Cell Cycle
Methylation
Response To Methotrexate
Spermatogenesis

Cell Death
Cell Growth
Cofactor Transport
Secretion
Meiosis Ii
Dna Hypomethylation
Brain Development

PTMs

Glycosylation
Methylation
Demethylation
Phosphorylation

Reduction
Deacetylation
Oxidation
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC19A2

References

PMID: 10542220 by Dutta B., et al. Cloning of the human thiamine transporter, a member of the folate transporter family.

PMID: 10391221 by Labay V., et al. Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness.