SLC19A1 Antibodies

AND SLC19A1 ELISA kits, SLC19A1 Proteins

Many biological assays use antibodies to detect SLC19A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC19A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC19A1 antibodies...

We validate the specificity of these antibodies to SLC19A1 by testing them on tissues known to express SLC19A1 positively and negatively. Browse below to find the SLC19A1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC19A1 Infographic by Boster Bio

All SLC19A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SLC19A1 Antibody Picoband®

2 Citations 1 Q&As

Human, Monkey, Mouse, Rat

$370
Cat # PB9504
100 μg/vial

Anti-RFC/SLC19A1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A01679-1
100 μg/vial

SLC19A1 (NM_194255) Human Over-expression Lysate

Human

$960
Cat # LS006573
100 µg

SLC19A1 Overview

Facts about Reduced folate transporter.

SLC19A1 3D structure. Source: alphafold

Reduced folate transporter (SLC19A1)

Transporter for the intake of folate.
Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.

Gene Information

Human
Gene Name:	SLC19A1
Uniprot:	P41440
Entrez:	6573

Family

Belongs to:

reduced folate carrier (RFC) transporter (TC 2.A.48) family

Alternative Names

CHMD; FLOT1; folate transporter 1; FOLT; FOLThuman reduced folate carrier (RFC)10Intestinal folate carrier 1; IFC1; IFC-1; Placental folate transporter; Reduced folate carrier protein; REFC; RFC; RFC1; SLC19A1; solute carrier family 19 (folate transporter), member 1; Solute carrier family 19 member 1

Molecular Weight

Mass (kDA):
64.868 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (45502517..45563140, complement)

Tissue Specificity

Placenta, liver, and to a much smaller extent, in lung.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
5,10-methylenetetrahydrofolate Reductase Deficiency
Leukemia
Neoplasms
Folic Acid Deficiency
Acute Lymphocytic Leukemia
L1 Acute Lymphoblastic Leukemia
Leukemia L1210
Arthritis
Malignant Neoplasm Of Breast
Rheumatoid Arthritis
Osteosarcoma
Down Syndrome

Lung Neoplasms
Congenital Abnormality
Lymphoma
Leukemia, T-cell
Myeloproliferative Syndrome, Transient
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Lung

Pathways

Transport
Methylation
Methotrexate Transport
Localization
Translation
Drug Resistance
Response To Methotrexate
Dna Methylation
Pathogenesis
Drug Transport
Cell Proliferation
Anion Transport
Gene Silencing

Intestinal Absorption
Cell Division
Cell Cycle
Chromosome Breakage
Thiamine Transport
Glycosylation
Dna Repair

PTMs

Methylation
Demethylation
Reduction
Glycosylation
Acetylation

Deglycosylation
Phosphorylation
Carboxylation
Biotinylation
Deacetylation

Gamma-carboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC19A1

References

PMID: 7826387 by Prasad P.D., et al. Molecular cloning of the human placental folate transporter.

PMID: 7615551 by Wong S.C., et al. Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells.

2 Publications of Boster SLC19A1 Antibodies & ELISA Kits

PubMed ID: , SLC19A1 transports immunoreactive cyclic dinucleotides
PubMed ID: 31511694 , SLC19A1 transports immunoreactive cyclic dinucleotides

*More publications can be found for each product on its corresponding product page