SLC18A2 Antibodies

AND SLC18A2 ELISA kits, SLC18A2 Proteins

Many biological assays use antibodies to detect SLC18A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC18A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC18A2 antibodies...

We validate the specificity of these antibodies to SLC18A2 by testing them on tissues known to express SLC18A2 positively and negatively. Browse below to find the SLC18A2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC18A2 Infographic by Boster Bio

All SLC18A2 Products

Product

Figures

Specificity

Applications

Price

Anti-SLC18A2 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02232
100ul

Anti-VMAT2 (SLC18A2) Mouse Monoclonal Antibody [Clone ID: OTI9E11]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$560
Cat # M02232
100 µl

VMAT2 (SLC18A2) (NM_003054) Human Over-expression Lysate

Human

$960
Cat # LS006571
100 µg

Anti-VMAT2/SLC18A2 Antibody Picoband™

Human, Rat

ELISA, WB

$370
Cat # A02232-1
100 μg/vial

SLC18A2 Overview

Facts about Synaptic vesicular amine transporter.

SLC18A2 3D structure. Source: alphafold

Synaptic vesicular amine transporter (SLC18A2)

Involved from the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles (PubMed:23363473).

Requisite for vesicular amine storage before secretion via exocytosis. .

Gene Information

Human
Gene Name:	SLC18A2
Uniprot:	Q05940
Entrez:	6571

Family

Belongs to:

major facilitator superfamily

Alternative Names

MGC120477; MNAT; monoamine neurotransmitter transporter; Monoamine transporter; SLC18A2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 member 2; SVAT; SVMT; SVMTMGC120478; synaptic vesicular amine transporter; VAT2; VAT2MGC26538; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; VMAT2

Molecular Weight

Mass (kDA):
55.713 kDA

Genomic Context


Human

Location:	10q25.3
Sequence:	10; NC_000010.11 (117241114..117279430)

Subcellular Localizations

Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Diseases

Parkinson Disease
Neurotoxicity Syndromes
Nerve Degeneration
Secondary Parkinson Disease
Nervousness
Schizophrenia
Depressive Disorder
Neoplasms
Malnutrition
Neurodegenerative Disorders
Mptp Poisoning
Disease Of Adrenal Medulla

Huntington Disease
Dementia
Mental Disorders
Lewy Body Disease
Diabetes Mellitus
Pheochromocytoma

Pathways

Transport
Innervation
Localization
Exocytosis
Cell Death
Secretion
Dopamine Uptake
Pathogenesis
Neuroprotection
Aging
Monoamine Transport
Glycosylation
Sensitization

Serotonin Uptake
Dopamine Transport
Regeneration
Acid Secretion
Insulin Secretion
Synaptic Transmission
Endocytosis

PTMs

Phosphorylation
Oxidation
Glycosylation
Reduction

Cleavage
Deglycosylation
Nitrosylation
Amidation

Methylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC18A2

References

PMID: 8095030 by Surratt C.K., et al. A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs.

PMID: 8245983 by Erickson J.D., et al. Functional identification and molecular cloning of a human brain vesicle monoamine transporter.