SLC16A7 Antibodies

AND SLC16A7 ELISA kits, SLC16A7 Proteins

Many biological assays use antibodies to detect SLC16A7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC16A7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC16A7 antibodies...

We validate the specificity of these antibodies to SLC16A7 by testing them on tissues known to express SLC16A7 positively and negatively. Browse below to find the SLC16A7 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC16A7 Infographic by Boster Bio

All SLC16A7 Products

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Specificity

Applications

Price

Anti-Monocarboxylate transporter 2 SLC16A7 Antibody

Human, Rat

$405
Cat # A05214
100ul

MCT2 (SLC16A7) (NM_004731) Human Over-expression Lysate

Human

$628
Cat # LS009194
100 µg

SLC16A7 Overview

Facts about Monocarboxylate transporter 2.

SLC16A7 3D structure. Source: alphafold

Monocarboxylate transporter 2 (SLC16A7)

Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Functions as high-affinity pyruvate transporter. .

Gene Information

Human
Gene Name:	SLC16A7
Uniprot:	O60669
Entrez:	9194

Family

Belongs to:

major facilitator superfamily

Alternative Names

MCT 2; MCT2solute carrier family 16 (monocarboxylic acid transporters), member 7; monocarboxylate transporter 2; Solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

Molecular Weight

Mass (kDA):
52.2 kDA

Genomic Context


Human

Location:	12q14.1
Sequence:	12; NC_000012.12 (59595934..59789841)

Tissue Specificity

Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypoglycemia
Carcinoma
Malignant Neoplasms
Neoplasms
Hypoxia
Ischemia
Brain Ischemia
Malignant Paraganglionic Neoplasm
Epilepsy
Nervousness
Cell Invasion
Obesity
Epilepsy, Temporal Lobe

Renal Tubular Acidosis
Diabetes Mellitus
Diabetes Mellitus, Experimental
Colorectal Neoplasms
Stasis
Colorectal Cancer
Cerebral Ischemia

Pathways

Transport
Lactate Transport
Localization
Synaptic Transmission
Nicotinate Transport
Reverse Transcription
Translation
Lactation
Neuroprotection
Glycolysis
Secretion
Cell Adhesion
Aerobic Respiration

Lactate Oxidation
Response To Methotrexate
Transcytosis
Spermatogenesis
Symport
Long-term Memory
Mating

PTMs

Carboxylation
Oxidation

Phosphorylation
Cleavage

Acetylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC16A7

References

PMID: 9786900 by Lin R.-Y., et al. Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.

PMID: 15505343 by Merezhinskaya N., et al. Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes.