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- Table of Contents
Facts about Monocarboxylate transporter 1.
Depending upon the tissue and on cicumstances, mediates the export or import of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet.
Human | |
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Gene Name: | SLC16A1 |
Uniprot: | P53985 |
Entrez: | 6566 |
Belongs to: |
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major facilitator superfamily |
FLJ36745; HHF7; MCT 1; MCT; MCT1; MCT1MGC44475; member 1; monocarboxylate transporter 1; SLC16A1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Mass (kDA):
53.944 kDA
Human | |
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Location: | 1p13.2 |
Sequence: | 1; NC_000001.11 (112911847..112956196, complement) |
Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.
Cell membrane; Multi-pass membrane protein.
PMID: 7835905 by Garcia C.K., et al. cDNA cloning of the human monocarboxylate transporter 1 and chromosomal localization of the SLC16A1 locus to 1p13.2-p12.
PMID: 11944921 by Cuff M.A., et al. The human monocarboxylate transporter, MCT1: genomic organization and promoter analysis.