Homeobox protein SIX2 Antibodies

AND SIX2 ELISA kits, Homeobox protein SIX2 Proteins

Many biological assays use antibodies to detect Homeobox protein SIX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein SIX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein SIX2 antibodies...

We validate the specificity of these antibodies to Homeobox protein SIX2 by testing them on tissues known to express SIX2 positively and negatively. Browse below to find the SIX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIX2 Infographic by Boster Bio

All SIX2 Products

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Product

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Specificity

Applications

Price

Anti-Homeobox protein SIX2 Six2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04092
100ul

SIX2 (NM_016932) Human Over-expression Lysate

Human

$628
Cat # LS010736
100 µg

SIX2 Overview

Facts about Homeobox protein SIX2.

SIX2 3D structure. Source: alphafold

Homeobox protein SIX2 (SIX2)

Transcription factor that plays a significant role in the development of many organs, including kidney, liver, skull and stomach. During kidney development, keeps cap mesenchyme multipotent nephron progenitor cells in an undifferentiated state by opposing the inductive signals generated from the ureteric bud and cooperates with WNT9B to promote renewing progenitor cells proliferation.

Acts through its interaction with TCF7L2 and OSR1 in a canonical Wnt signaling independent manner preventing transcription of differentiation genes in cap mesenchyme such as WNT4. Additionally acts independently of OSR1 to activate expression of many cap mesenchyme genes, such as itself, GDNF and OSR1.

Gene Information

Human
Gene Name:	SIX2
Uniprot:	Q9NPC8
Entrez:	10736

Family

Belongs to:

SIX/Sine oculis homeobox family

Alternative Names

homeobox protein SIX2; sine oculis homeobox (Drosophila) homolog 2; sine oculis homeobox homolog 2 (Drosophila); Sine oculis homeobox homolog 2; SIX homeobox 2