This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Homeobox protein SIX1.
Based on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation.
Human | |
---|---|
Gene Name: | SIX1 |
Uniprot: | Q15475 |
Entrez: | 6495 |
Belongs to: |
---|
SIX/Sine oculis homeobox family |
BOS3; deafness, autosomal dominant 23; DFNA23; homeobox protein SIX1; sine oculis homeobox (Drosophila) homolog 1; sine oculis homeobox homolog 1 (Drosophila); Sine oculis homeobox homolog 1; SIX homeobox 1; TIP39
Mass (kDA):
32.21 kDA
Human | |
---|---|
Location: | 14q23.1 |
Sequence: | 14; NC_000014.9 (60643421..60649489, complement) |
Specifically expressed in skeletal muscle.
Nucleus. Cytoplasm.
PMID: 8617500 by Boucher C.A., et al. Cloning of the human SIX1 gene and its assignment to chromosome 14.
PMID: 10801845 by Ford H.L., et al. Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein.