SHOX Antibodies

AND SHOX ELISA kits, SHOX Proteins

Many biological assays use antibodies to detect SHOX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SHOX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SHOX antibodies...

We validate the specificity of these antibodies to SHOX by testing them on tissues known to express SHOX positively and negatively. Browse below to find the SHOX antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SHOX Infographic by Boster Bio

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Anti-Short stature homeobox protein SHOX Antibody

Human, Mouse, Rat

$405
Cat # A02956
100ul

SHOX Overview

Facts about Short stature homeobox protein.

SHOX 3D structure. Source: alphafold

Short stature homeobox protein (SHOX)

Controls basic aspects of growth and development. .

Gene Information

Human
Gene Name:	SHOX
Uniprot:	O15266
Entrez:	6473

Family

Belongs to:

paired homeobox family

Alternative Names

GCFXX-linked; PHOGShort stature homeobox-containing protein; Pseudoautosomal homeobox-containing osteogenic protein; short stature homeobox protein; short stature homeobox; SHOXY

Molecular Weight

Mass (kDA):
32.236 kDA

Genomic Context


Human

Location:	Xp22.33 and Yp11.2
Sequence:	X\|Y; NC_000023.11 (624344..659411)

Tissue Specificity

SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.

Subcellular Localizations

Nucleus.

Diseases

Dwarfism
Leri-weill Dyschondrosteosis
Turner Syndrome
Growth Disorders
Haploinsufficiency
Osteochondrodysplasias
Dysplasia
Madelung's Deformity
Langer Mesomelic Dysplasia Syndrome
Congenital Abnormality

Sex Chromosome Aberrations
Skeletal Dysplasia
Growth Retardation
Shwachman Syndrome
Cytogenetic Abnormality

Interacting Proteins

SOX5
SOX6

Pathways

Limb Development
Meiosis
Cell Proliferation
Localization
Ossification
Translation
Bone Development
Endochondral Ossification
Metaphase
Pathogenesis
Brain Development
Interphase
Menarche

Male Meiosis
Dna Methylation
Methylation
Transposition
Neurogenesis
Regulation Of Gene Expression
Sex Determination

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHOX

References

PMID: 9140395 by Rao E., et al. Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome.

PMID: 9259282 by Ellison J.W., et al. PHOG, a candidate gene for involvement in the short stature of Turner syndrome.