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- Table of Contents
Facts about SHC SH2 domain-binding protein 1.
Acts as a positive regulator of FGF signaling in neural progenitor cells. .
Mouse | |
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Gene Name: | Shcbp1 |
Uniprot: | Q9Z179 |
Entrez: | 20419 |
Belongs to: |
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No superfamily |
SHC SH2 domain-binding protein 1
Mass (kDA):
75.917 kDA
Mouse | |
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Location: | 8|8 A1.1 |
Sequence: | 8; |
Expressed in spleen, lung and heart with higher expression in testis. No expression in brain, liver and skeletal muscle. Elevated expression in actively cycling cells.
PMID: 10086341 by Schmandt R., et al. Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells.
PMID: 22508726 by Chen J., et al. The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling.