Endophilin-B1 Antibodies

AND SH3GLB1 ELISA kits, Endophilin-B1 Proteins

Many biological assays use antibodies to detect Endophilin-B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endophilin-B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endophilin-B1 antibodies...

We validate the specificity of these antibodies to Endophilin-B1 by testing them on tissues known to express SH3GLB1 positively and negatively. Browse below to find the SH3GLB1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH3GLB1 Infographic by Boster Bio

All SH3GLB1 Products

Product

Figures

Specificity

Applications

Price

Anti-Bif SH3GLB1 Antibody

Human, Mouse

ELISA, ICC, WB

$449
Cat # A04792
0.1 mg

Anti-Endophilin-B1 SH3GLB1 Antibody

Human

IF, ICC, WB

$405
Cat # A04792-1
100ul

Bif (SH3GLB1) (NM_016009) Human Recombinant Protein

$1249
Cat # PROTQ9Y371
20 µg

Bif (SH3GLB1) (NM_016009) Human Over-expression Lysate

Human

$628
Cat # LS051100
100 µg

SH3GLB1 Overview

Facts about Endophilin-B1.

SH3GLB1 3D structure. Source: alphafold

Endophilin-B1 (SH3GLB1)

May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells (By similarity).

May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588).

Gene Information

Human
Gene Name:	SH3GLB1
Uniprot:	Q9Y371
Entrez:	51100

Family

Belongs to:

endophilin family

Alternative Names

Bax-interacting factor 1; Bif1; Bif-1; Bif-1dJ612B15.2; CGI-61; Endophilin B1; endophilin-B1; KIAA0491endophilin B1; SH3 domain-containing GRB2-like protein B1; SH3-containing protein SH3GLB1; SH3-domain GRB2-like endophilin B1; SH3-domain, GRB2-like, endophilin B1; SH3GLB1

Molecular Weight

Mass (kDA):
40.796 kDA

Genomic Context


Human

Location:	1p22.3
Sequence:	1; NC_000001.11 (86704570..86748184)

Tissue Specificity

Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.

Subcellular Localizations

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane. Midbody. Association with the Golgi apparatus depends on the cell type (By similarity). Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes (PubMed:17891140).

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Adenocarcinoma
Mammary Neoplasms
Stomach Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Immunologic Deficiency Syndromes
Colorectal Neoplasms
Carcinogenesis
Malignant Neoplasm Of Prostate

Mutation Abnormality
Intraepithelial Neoplasia
Neoplasms, Experimental
Aneuploidy
Benign Prostatic Hypertrophy
Carcinoma In Situ
Lymphoma

Interacting Proteins

BAX
CMTM5
COQ8A
FUNDC1
GADD45A

PSMA1
SH3GLB2
TFIP11
UVRAG
ZNF576

Pathways

Autophagy
Cell Death
Endocytosis
Programmed Cell Death
Cellular Homeostasis
Regulation Of Autophagy
Response To Nutrient
Clathrin-mediated Endocytosis
Virion Assembly
Cell Migration
Cytokinesis
Cell Division

Translation
Lipid Binding
Organelle Fission
Induction Of Apoptosis
Localization
Receptor Internalization
Necrotic Cell Death

PTMs

Phosphorylation

Research Areas

Apoptosis
Mitochondrial-Mediated Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH3GLB1

References

PMID: 11161816 by Pierrat B., et al. SH3GLB, a new endophilin-related protein family featuring an SH3 domain.

PMID: 11259440 by Cuddeback S.M., et al. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax.