SH3BP2 Antibodies

AND SH3BP2 ELISA kits, SH3BP2 Proteins

Many biological assays use antibodies to detect SH3BP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH3BP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH3BP2 antibodies...

We validate the specificity of these antibodies to SH3BP2 by testing them on tissues known to express SH3BP2 positively and negatively. Browse below to find the SH3BP2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH3BP2 Infographic by Boster Bio

All SH3BP2 Products

Product

Figures

Specificity

Applications

Price

Anti-Phospho-SH3BP2 S427 Antibody

3 Q&As

Human, Mouse, Rat

ELISA, WB

$599
Cat # P04008
100ug

Anti-3BP2 SH3BP2 Antibody

Human

ELISA, WB

$380
Cat # A04008
100ul

SH3BP2 (NM_001122681) Human Recombinant Protein

$1249
Cat # PROTP78314
20 µg

SH3BP2 (NM_003023) Human Over-expression Lysate

Human

$628
Cat # LS006452
100 µg

Anti-3BP2/SH3BP2 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04008-1
100 µg/vial

SH3BP2 Overview

Facts about SH3 domain-binding protein 2.

SH3BP2 3D structure. Source: alphafold

SH3 domain-binding protein 2 (SH3BP2)

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes into the cytoplasmic membrane in a phosphorylation dependent mechanism.

Gene Information

Human
Gene Name:	SH3BP2
Uniprot:	P78314
Entrez:	6452

Family

Belongs to:

No superfamily

Alternative Names

Abl-SH3 binding protein 2; Cherubism; CRBM; CRPM; FLJ42079; FLJ54978,3BP-2,3BP2; RES4-23; SH3 domain-binding protein 2; SH3-domain binding protein 2; TNFAIP3 interacting protein 2

Molecular Weight

Mass (kDA):
62.244 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (2793085..2841096)

Tissue Specificity

Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.

Diseases

Cherubism
Inflammation
Edema
Giant Cell Granuloma
Granuloma
Jaw Diseases
Noonan Syndrome
Osteopenia
Neoplasms
Bone Diseases
Granuloma, Giant Cell Reparative
Dysplasia

Root Resorption
Hereditary Diseases
Malignant Neoplasms
Pain
Osteoporosis
Noonan-like/multiple Giant Cell Lesion Syndrome (disorder)
Osteomyelitis

Interacting Proteins

DBNL
KIT
SH3KBP1
TNKS2
VAV1

VAV2

Pathways

Bone Resorption
Pathogenesis
Osteoclast Differentiation
Secretion
Cell Activation
Osteoblast Differentiation
Immune Response
Mast Cell Activation
Bone Remodeling
Cell Migration
Gene Silencing
Cytokine Secretion
Chemotaxis

Regulation Of Bone Resorption
Cell Cycle
Innate Immune Response
Cytolysis
Cell Killing
Cell Development
Neutrophil Chemotaxis

PTMs

Phosphorylation
Dephosphorylation

Demethylation
Methylation

Ribosylation

Research Areas

Cell Biology
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH3BP2

References

PMID: 9299232 by Bell S.M., et al. Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer.

PMID: 9734812 by Hadano S., et al. The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3.