Beta-sarcoglycan Antibodies

AND SGCB ELISA kits, Beta-sarcoglycan Proteins

Many biological assays use antibodies to detect Beta-sarcoglycan, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Beta-sarcoglycan in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Beta-sarcoglycan antibodies...

We validate the specificity of these antibodies to Beta-sarcoglycan by testing them on tissues known to express SGCB positively and negatively. Browse below to find the SGCB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SGCB Infographic by Boster Bio

All SGCB Products

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Product

Figures

Specificity

Applications

Price

Anti-Sarcoglycan-Beta (V136) SGCB Antibody

Human, Mouse, Rat

IHC

$405
Cat # A07064
100ul

Anti-Sarcoglycan-Beta SGCB Antibody

Human, Mouse, Rat

$405
Cat # A07064-1
100ul

Human SGCB Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ16585
Starting from 20ug

beta Sarcoglycan (SGCB) (NM_000232) Human Over-expression Lysate

Human

$628
Cat # LS006443
100 µg

SGCB Overview

Facts about Beta-sarcoglycan.

SGCB 3D structure. Source: alphafold

Beta-sarcoglycan (SGCB)

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. .

Gene Information

Human
Gene Name:	SGCB
Uniprot:	Q16585
Entrez:	6443

Family

Belongs to:

sarcoglycan beta/delta/gamma/zeta family

Alternative Names

43 kDa dystrophin-associated glycoprotein; 43DAG; A3b; A3bbeta-SG; beta Sarcoglycan; beta-Sarcoglycan; beta-sarcoglycan(43kD dystrophin-associated glycoprotein); Beta-SG; LGMD2E; limb girdle muscular dystrophy 2E (non-linked families); Sarcoglycan beta; sarcoglycan, beta (43kD dystrophin-associated glycoprotein); sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); SGC; SGCB

Molecular Weight

Mass (kDA):
34.777 kDA

Genomic Context


Human

Location:	4q12
Sequence:	4; NC_000004.12 (52020706..52038299, complement)

Tissue Specificity

Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.

Subcellular Localizations

Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.

Diseases

Muscular Dystrophy
Dystrophy
Muscular Dystrophies, Limb-girdle
Sarcoglycanopathies
Cardiomyopathies
Weakness
Muscular Dystrophy, Duchenne
Myopathy
Hereditary Diseases
Muscle Weakness
Chest Pain
Cystic Fibrosis

Cardiac Arrhythmia
Hypoxia
Cardiac Complication
Cardiovascular Diseases
Fibrosis
Becker Muscular Dystrophy
Congenital Anomaly Of Brain

Pathways

Transport
Translation
Cardiac Conduction
Spermatogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SGCB

References

PMID: 7581449 by Boennemann C.G., et al. Beta-sarcoglycan (A3b) mutations cause autosomal recessive muscular dystrophy with loss of the sarcoglycan complex.

PMID: 7581448 by Lim L.E., et al. Beta-sarcoglycan: characterization and role in limb-girdle muscular dystrophy linked to 4q12.