SFRP4 Antibodies

AND SFRP4 ELISA kits, SFRP4 Proteins

Many biological assays use antibodies to detect SFRP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SFRP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SFRP4 antibodies...

We validate the specificity of these antibodies to SFRP4 by testing them on tissues known to express SFRP4 positively and negatively. Browse below to find the SFRP4 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SFRP4 Infographic by Boster Bio

All SFRP4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SFRP4 Antibody Picoband®

6 Q&As

Human, Rat

$370
Cat # RP1067
100 μg/vial

Anti-SFRP4 Antibody Picoband®

Human

ELISA, IHC, WB

$370
Cat # PB9888
100 μg/vial

Anti-SFRP4 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A03147
100ul

Anti-SFRP4 Antibody

Human, Mouse, Rat

Flow Cytometry, WB

$405
Cat # A03147-1
100ul

Human SFRP4 Recombinant Protein

SDS-PAGE

$350
Cat # PROTQ6FHJ7
Starting from 10ug

Anti-SFRP4 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03147-1
100 μl/vial

SFRP4 (NM_003014) Human Over-expression Lysate

Human

$628
Cat # LS006424
100 µg

SFRP4 Overview

Facts about Secreted frizzled-related protein 4.

SFRP4 3D structure. Source: alphafold

Secreted frizzled-related protein 4 (SFRP4)

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity).

SFRP4 plays a role in bone morphogenesis. May also function as a regulator of adult uterine morphology and function.

Gene Information

Human
Gene Name:	SFRP4
Uniprot:	Q6FHJ7
Entrez:	6424

Family

Belongs to:

secreted frizzled-related protein (sFRP) family

Alternative Names

DDC-4; Frizzled protein, human endometrium; FRP-4; FRP-AP; frpHE; FRPHEMGC26498; FrzB2; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; sFRP4; sFRP-4

Molecular Weight

Mass (kDA):
39.827 kDA

Genomic Context


Human

Location:	7p14.1
Sequence:	7; NC_000007.14 (37905932..37916817, complement)

Tissue Specificity

Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, expression levels are inversely correlated with expression of CTNNB1 (at protein level).

Subcellular Localizations

Secreted. Cytoplasmic in ovarian tumor cells.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Carcinogenesis
Leukemia
Malignant Paraganglionic Neoplasm
Endometrial Polyp
Adenocarcinoma
Hyperplasia
Colorectal Cancer
Mammary Neoplasms
Hypophosphatemia

Malignant Squamous Cell Neoplasm
Tissue Adhesions
Endometrial Neoplasms
Osteomalacia
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Colorectal Neoplasms

Pathways

Methylation
Pathogenesis
Cell Proliferation
Dna Methylation
Localization
Demethylation
Cell Cycle
Cell Growth
Ovulation
Excretion
Decidualization
Oncogenesis
Cell Death

Angiogenesis
Secretion
Cell Adhesion
Cell Migration
Osteoblast Differentiation
Embryo Implantation
Mismatch Repair

PTMs

Methylation
Demethylation
Phosphorylation

Reduction
Deacetylation
Cleavage

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SFRP4

References

PMID: 10211996 by Abu-Jawdeh G.M., et al. Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy.

PMID: 12952927 by Berndt T., et al. Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent.