This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Splicing factor 3B subunit 1.
Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex (PubMed:10882114).
Human | |
---|---|
Gene Name: | SF3B1 |
Uniprot: | O75533 |
Entrez: | 23451 |
Belongs to: |
---|
SF3B1 family |
Hsh155; pre-mRNA processing 10; pre-mRNA splicing factor SF3b, 155 kDa subunit; Pre-mRNA-splicing factor SF3b 155 kDa subunit; Prp10; PRPF10; SAP 155; SAP155splicing factor 3b, subunit 1, 155kD; SF3B155; SF3b155PRP10; spliceosome associated protein 155; Spliceosome-associated protein 155; splicing factor 3B subunit 1; splicing factor 3b, subunit 1, 155kDa
Mass (kDA):
145.83 kDA
Human | |
---|---|
Location: | 2q33.1 |
Sequence: | 2; NC_000002.12 (197389784..197435093, complement) |
Nucleus. Nucleus speckle. During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm.
PMID: 9585501 by Wang C., et al. Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis.
PMID: 10882114 by Das R., et al. Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.