Serine incorporator 3 Antibodies

AND SERINC3 ELISA kits, Serine incorporator 3 Proteins

Many biological assays use antibodies to detect Serine incorporator 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Serine incorporator 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Serine incorporator 3 antibodies...

We validate the specificity of these antibodies to Serine incorporator 3 by testing them on tissues known to express SERINC3 positively and negatively. Browse below to find the SERINC3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERINC3 Infographic by Boster Bio

All SERINC3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SERC3 SERINC3 Antibody

Human, Mouse, Rat

IF, WB

$360
Cat # A05936
100 µl

Anti-TDE1 (R392) SERINC3 Antibody

Human, Mouse, Rat

IHC

$405
Cat # A05936-1
100ul

Anti-SERINC3 Antibody Picoband®

Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A05936-2
100 μg/vial

SERINC3 (NM_006811) Human Recombinant Protein

$813
Cat # PROTQ13530
20 µg

SERINC3 (NM_006811) Human Over-expression Lysate

Human

$628
Cat # LS010955
100 µg

SERINC3 Overview

Facts about Serine incorporator 3.

SERINC3 3D structure. Source: alphafold

Serine incorporator 3 (SERINC3)

Restriction factor needed to restrict infectivity of lentiviruses, such as HIV-1: functions by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734).

Gene Information

Human
Gene Name:	SERINC3
Uniprot:	Q13530
Entrez:	10955

Family

Belongs to:

TDE1 family

Alternative Names

AIGP1; DIFF33tumor differentially expressed 1; placental transmembrane protein (mouse testicular tumor differentiallyexpressed); SBBI99; serine incorporator 3; TDE; TDE1Tumor differentially expressed protein 1; TMS-1; transmembrane protein SBBI99; tumour differentially expressed 1

Molecular Weight

Mass (kDA):
52.58 kDA

Genomic Context


Human

Location:	20q13.12
Sequence:	20; NC_000020.11 (44496221..44522116, complement)

Tissue Specificity

Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region. (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable).

Diseases

Neoplasms
Cell Transformation, Neoplastic
Testicular Neoplasms
Malignant Neoplasms
Colorectal Neoplasms

Pathways

Localization
Reverse Transcription
Programmed Cell Death
Cell Death
Cell Differentiation
Glycosylation
Contact Inhibition

Oncogenesis

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERINC3

References

PMID: 10559794 by Bossolasco M., et al. The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue.

PMID: 26416733 by Usami Y., et al. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef.