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- Table of Contents
Facts about Thioredoxin reductase-like selenoprotein T.
Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity). Plays a role in fibroblast anchorage and redox regulation (By similarity).
Human | |
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Gene Name: | SELENOT |
Uniprot: | P62341 |
Entrez: | 51714 |
Belongs to: |
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SelWTH family |
Thioredoxin reductase-like selenoprotein T
Mass (kDA):
22.324 kDA
Human | |
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Location: | 3q25.1 |
Sequence: | 3; NC_000003.12 (150603321..150630436) |
Ubiquitous. Highly expressed in the endocrine pancreas.
Endoplasmic reticulum membrane; Single-pass membrane protein.
PMID: 10567350 by Kryukov G.V., et al. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements.
PMID: 23913443 by Prevost G., et al. The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human beta-cells and its targeted inactivation impairs glucose tolerance.