Protein sel-1 homolog 1 Antibodies

AND SEL1L ELISA kits, Protein sel-1 homolog 1 Proteins

Many biological assays use antibodies to detect Protein sel-1 homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein sel-1 homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein sel-1 homolog 1 antibodies...

We validate the specificity of these antibodies to Protein sel-1 homolog 1 by testing them on tissues known to express SEL1L positively and negatively. Browse below to find the SEL1L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEL1L Infographic by Boster Bio

All SEL1L Products

Product

Figures

Specificity

Applications

Price

Anti-Protein sel-1 homolog 1 SEL1L Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A03343
100ul

Anti-SEL1L Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03343-2
100 μg/vial

SEL1L Overview

Facts about Protein sel-1 homolog 1.

SEL1L 3D structure. Source: alphafold

Protein sel-1 homolog 1 (SEL1L)

Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509). Enhances SYVN1 stability.

Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells.

Gene Information

Human
Gene Name:	SEL1L
Uniprot:	Q9UBV2
Entrez:	6400

Family

Belongs to:

sel-1 family

Alternative Names

IBD2; PRO1063; protein sel-1 homolog 1; sel-1 (suppressor of lin-12, C.elegans)-like; sel-1 suppressor of lin-12-like (C. elegans); sel-1 suppressor of lin-12-like 1; sel-1L; SEL1L1; SEL1-LIKE; Suppressor of lin 12 (sel-1), C. elegans, homolog of; Suppressor of lin-12-like protein 1; TSA305

Molecular Weight

Mass (kDA):
88.755 kDA

Genomic Context


Human

Location:	14q31.1
Sequence:	14; NC_000014.9 (81471547..81533861, complement)

Tissue Specificity

Highly expressed in pancreas.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Dislocations
Diabetes Mellitus
Adenocarcinoma
Alzheimer's Disease
Diabetes Mellitus, Insulin-dependent
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Malignant Neoplasm Of Breast
Cytomegalovirus Infections

Cell Transformation, Neoplastic
Lung Neoplasms
Dysplasia
Tumor Progression
Parkinson Disease
Physiological Stress

Interacting Proteins

FOXRED2

Pathways

Secretion
Transport
Pathogenesis
Cell Differentiation
Cell Death
Protein Folding
Protein Secretion
Secretory Pathway
Insulin Secretion
Endocytosis
Localization
Notch Signaling Pathway

Protein Maturation
Cell Fate Determination
Reverse Transcription
Translation
Cell Cycle
Invasive Growth
Nuclear Import

PTMs

Glycosylation
Cleavage

Ubiquitination
Carboxylation

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEL1L

References

PMID: 10496078 by Harada Y., et al. Complete cDNA sequence and genomic organization of a human pancreas- specific gene homologous to Caenorhabditis elegans sel-1.

PMID: 10746565 by Biunno I., et al. SEL1L, the human homolog of C. elegans sel-1: refined physical mapping, gene structure and identification of polymorphic markers.