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- Table of Contents
Facts about Secreted and transmembrane protein 1.
Human | |
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Gene Name: | SECTM1 |
Uniprot: | Q8WVN6 |
Entrez: | 6398 |
Belongs to: |
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SECTM family |
CD7 Ligand; K12secreted and transmembrane protein 1; Protein K12; Protein K-12; secreted and transmembrane 1; SECTM1; type 1a transmembrane protein
Mass (kDA):
27.039 kDA
Human | |
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Location: | 17q25.3 |
Sequence: | 17; NC_000017.11 (82321024..82333951, complement) |
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.
Cell membrane; Single-pass type I membrane protein. Secreted.
PMID: 9480746 by Slentz-Kesler K.A., et al. Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms.
PMID: 10652336 by Lyman S.D., et al. Identification of CD7 as a cognate of the human K12 (SECTM1) protein.