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- Table of Contents
Facts about Protein transport protein Sec24B.
Plays a central role in cargo selection within the COPII complex and collectively with SEC24A might have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and might also recognize conformational epitopes (PubMed:17499046, PubMed:18843296).
Human | |
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Gene Name: | SEC24B |
Uniprot: | O95487 |
Entrez: | 10427 |
Belongs to: |
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SEC23/SEC24 family |
member B; MGC48822; protein transport protein Sec24B; SEC24 family, member B (S. cerevisiae); SEC24; Sec24-related protein B; secretory protein 24
Mass (kDA):
137.418 kDA
Human | |
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Location: | 4q25 |
Sequence: | 4; NC_000004.12 (109433715..109540896) |
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
PMID: 10075675 by Pagano A., et al. Sec24 proteins and sorting at the endoplasmic reticulum.
PMID: 17499046 by Mancias J.D., et al. The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.