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- Table of Contents
Facts about Protein transport protein Sec24A.
Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity when compared with SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE themes and may also recognize conformational epitopes (PubMed:17499046, PubMed:18843296).
Human | |
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Gene Name: | SEC24A |
Uniprot: | O95486 |
Entrez: | 10802 |
Belongs to: |
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SEC23/SEC24 family |
member A; protein transport protein Sec24A; SEC24 family, member A (S. cerevisiae); SEC24-related protein A
Mass (kDA):
119.749 kDA
Human | |
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Location: | 5q31.1 |
Sequence: | 5; NC_000005.10 (134647757..134727909) |
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
PMID: 10075675 by Pagano A., et al. Sec24 proteins and sorting at the endoplasmic reticulum.
PMID: 20427317 by Bonnon C., et al. Selective export of human GPI-anchored proteins from the endoplasmic reticulum.