SEC22B Antibodies

AND SEC22B ELISA kits, SEC22B Proteins

Many biological assays use antibodies to detect SEC22B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC22B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC22B antibodies...

We validate the specificity of these antibodies to SEC22B by testing them on tissues known to express SEC22B positively and negatively. Browse below to find the SEC22B antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEC22B Infographic by Boster Bio

All SEC22B Products

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Product

Figures

Specificity

Applications

Price

Anti-SEC22B/Sec22L1 Antibody

3 Q&As

Human, Mouse, Rat

IHC, WB

$399
Cat # A06284
100μl

Human SEC22B Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO75396
Starting from 20ug

SEC22L1 (SEC22B) (NM_004892) Human Over-expression Lysate

Human

$628
Cat # LS009554
100 µg

Anti-SEC22B Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A06284-2
100 μg/vial

SEC22B Overview

Facts about Vesicle-trafficking protein SEC22b.

SEC22B 3D structure. Source: alphafold

Vesicle-trafficking protein SEC22b (SEC22B)

SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex in addition to Golgi-derived retrograde transport vesicles with the ER. .

Gene Information

Human
Gene Name:	SEC22B
Uniprot:	O75396
Entrez:	9554

Family

Belongs to:

synaptobrevin family

Alternative Names

ERS24; ERS-24sec22b; SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene); SEC22 vesicle trafficking protein homolog B (S. cerevisiae); SEC22 vesicle trafficking protein-like 1 (S. cerevisiae); SEC22 vesicle trafficking protein-like 1; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1; SEC22, vesicle trafficking protein (S. cerevisiae)-like 1; SEC22L1ER-Golgi SNARE of 24 kDa; vesicle-trafficking protein SEC22b

Molecular Weight

Mass (kDA):
24.593 kDA

Genomic Context


Human

Location:	1p12
Sequence:	1; NC_000001.11 (120150898..120176520, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome. Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).

Diseases

Legionnaires' Disease
Murine Hepatitis
Impaired Phagocytosis
Toxoplasmosis
Escherichia Coli Infections
Stomatitis
Parkinson Disease
Dysplasia
Osteoarthropathy
Neoplasms
Cell Invasion
Hereditary Diseases
Coronavirus Infections

Liver Carcinoma
Hepatitis
Osteochondrodysplasias
Tissue Adhesions
Atherosclerosis
Physiological Stress
Vesicular Stomatitis

Interacting Proteins

STX18
STX4

Pathways

Transport
Membrane Fusion
Secretory Pathway
Phagocytosis
Localization
Secretion
Snare Complex Assembly
Vesicle Transport
Endocytosis
Vesicle Docking
Golgi To Plasma Membrane Transport
Clathrin-mediated Endocytosis
Phagosome Formation

Phagosome Maturation
Protein Targeting
Glycosylation
Oocyte Maturation
Snare Complex Disassembly
Vesicle Fusion
Protein Glycosylation

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC22B

References

PMID: 9653160 by Mao M., et al. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning.

PMID: 15272311 by Nakajima K., et al. Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.