SCN2A Antibodies

AND SCN2A ELISA kits, SCN2A Proteins

Many biological assays use antibodies to detect SCN2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SCN2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SCN2A antibodies...

We validate the specificity of these antibodies to SCN2A by testing them on tissues known to express SCN2A positively and negatively. Browse below to find the SCN2A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCN2A Infographic by Boster Bio

All SCN2A Products

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Anti-SCN2A Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A01735-2
100 μg/vial

Anti-Scn2a Antibody Picoband®

Mouse, Rat

$370
Cat # A01735-3
100 μg/vial

SCN2A Overview

Facts about Sodium channel protein type 2 subunit alpha.

SCN2A 3D structure. Source: alphafold

Sodium channel protein type 2 subunit alpha (SCN2A)

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

Gene Information

Human
Gene Name:	SCN2A
Uniprot:	Q99250
Entrez:	6326

Family

Belongs to:

sodium channel (TC 1.A.1.10) family

Alternative Names

Sodium channel protein type 2 subunit alpha

Molecular Weight

Mass (kDA):
227.975 kDA

Genomic Context


Human

Location:	2q24.3
Sequence:	2; NC_000002.12 (165208056..165392310)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

PTMs

Disulfide bond
Glycoprotein

Isopeptide bond
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCN2A

References

PMID: 1325650 by Ahmed C.M., et al. Primary structure, chromosomal localization, and functional expression of a voltage-gated sodium channel from human brain.

PMID: 11245985 by Kasai N., et al. Genomic structures of SCN2A and SCN3A -- candidate genes for deafness at the DFNA16 locus.