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Sciellin Antibodies

AND SCEL ELISA kits, Sciellin Proteins

Many biological assays use antibodies to detect Sciellin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sciellin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sciellin antibodies...

We validate the specificity of these antibodies to Sciellin by testing them on tissues known to express SCEL positively and negatively. Browse below to find the SCEL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCEL Infographic by Boster Bio

SCEL protein infographic

All SCEL Products

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Product

Figures

Specificity

Applications

Price

SCEL (NM_003843) Human Recombinant Protein

$1249
Cat # PROTO95171
20 µg

SCEL (NM_003843) Human Over-expression Lysate

Human

$628
Cat # LS008796
100 µg

SCEL Overview

Facts about Sciellin.

SCEL 3D structure

SCEL 3D structure. Source: alphafold

Sciellin (SCEL)

May function in the regulation or assembly of proteins at the cornified envelope. The LIM domain might be involved in homotypic or heterotypic associations and might function to localize sciellin to the cornified envelope.

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Gene Information

Human
Gene Name:	SCEL
Uniprot:	O95171
Entrez:	8796

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

FLJ21667; MGC22531; sciellin

Molecular Weight

Mass (kDA):
77.552 kDA

Molecular Weight

Genomic Context


Human

Location:	13q22.3
Sequence:	13; NC_000013.11 (77535674..77645263)

Subcellular Localizations

Cytoplasm. Membrane. May become cross-linked to membrane proteins by transglutaminase.

Subcellular Localization

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Malignant Squamous Cell Neoplasm
Sclerosis
Tongue Neoplasms
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Carcinogenesis
Tongue Squamous Cell Carcinoma
Papillary Thyroid Carcinoma
Chimera Disorder

Esophageal Neoplasms
Cell Invasion
Denys-drash Syndrome
Psoriasis
Follicular Thyroid Carcinoma
Atheroma
Tissue Adhesions

Disease

Interacting Proteins

FXR2
GOLGA2
KIFC3
MTUS2
NMI

TSGA10

Interacting Proteins

Pathways

Localization
Keratinization
Transport
Cornification
Chemotaxis
Extracellular Matrix Organization
Response To Hydrogen Peroxide

Keratinocyte Differentiation
Cellular Response To Hydrogen Peroxide

Pathways

PTMs

Acetylation

Phosphoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCEL

References

PMID: 9813070 by Champliaud M.-F., et al. cDNA cloning and characterization of sciellin, a LIM domain protein of the keratinocyte cornified envelope.