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- Table of Contents
Facts about GTP-binding protein SAR1b.
Involved in the selection of the protein freight and the assembly of the COPII coat complex. .
Human | |
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Gene Name: | SAR1B |
Uniprot: | Q9Y6B6 |
Entrez: | 51128 |
Belongs to: |
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small GTPase superfamily |
2310075M17Rik; ANDD; CMRD; EC 3.6.5; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; SAR1 homolog B (S. cerevisiae); SAR1a gene homolog (S. cerevisiae) 2; SAR1a gene homolog 2 (S. cerevisiae); SAR1a gene homolog 2; SARA2GTBPB; SARB
Mass (kDA):
22.41 kDA
Human | |
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Location: | 5q31.1 |
Sequence: | 5; NC_000005.10 (134601149..134632828, complement) |
Expressed in many tissues including small intestine, liver, muscle and brain.
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
PMID: 12692552 by Jones B., et al. Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders.
PMID: 17309654 by Annesi G., et al. SIL1 and SARA2 mutations in Marinesco-Sjogren and chylomicron retention diseases.