S-arrestin Antibodies

AND SAG ELISA kits, S-arrestin Proteins

Many biological assays use antibodies to detect S-arrestin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with S-arrestin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop S-arrestin antibodies...

We validate the specificity of these antibodies to S-arrestin by testing them on tissues known to express SAG positively and negatively. Browse below to find the SAG antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SAG Infographic by Boster Bio

All SAG Products

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Figures

Specificity

Applications

Price

Anti-Retinal S antigen/SAG Antibody Picoband®

1 Q&As

Human, Mouse, Rat

ELISA, WB

$370
Cat # A03775
100 μg/vial

Retinal S antigen (SAG) (NM_000541) Human Recombinant Protein

$1062
Cat # PROTP10523
20 µg

Anti-Retinal S antigen (SAG) Mouse Monoclonal Antibody [Clone ID: OTI7A12]

Human, Mouse, Rat

$523
Cat # M03775-1
100 µl

SAG Overview

Facts about S-arrestin.

SAG 3D structure. Source: alphafold

S-arrestin (SAG)

Binds to photoactivated, phosphorylated RHO and terminates RHO indicating via G-proteins by competing with G- proteins for the same binding site on RHO (By similarity). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (PubMed:9565049).

Gene Information

Human
Gene Name:	SAG
Uniprot:	P10523
Entrez:	6295

Family

Belongs to:

arrestin family

Alternative Names

arrestin 1; RP47,48 kDa protein; S-antigen; retina and pineal gland (arrestin); S-arrestin; visual arrestin

Molecular Weight

Mass (kDA):
45.12 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233307816..233347066)

Tissue Specificity

Detected in retina, in the proximal portion of the outer segment of rod photoreceptor cells (at protein level).

Subcellular Localizations

Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. Highly expressed in photoreceptor outer segments in light-exposed retina. Evenly distributed throughout rod photoreceptor cells in dark-adapted retina (By similarity). Predominantly dectected at the proximal region of photoreceptor outer segments, near disk membranes (PubMed:3720866).