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- Table of Contents
Facts about SUMO-activating enzyme subunit 1.
.
Human | |
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Gene Name: | SAE1 |
Uniprot: | Q9UBE0 |
Entrez: | 10055 |
Belongs to: |
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ubiquitin-activating E1 family |
AOS1; AOS1activator of SUMO1; FLJ3091; HSPC140; SAE1; SUA1; SUA1sentrin/SUMO-activating protein AOS1; SUMO Activating Enzyme E1 (SAE1/UBA2); SUMO-1 activating enzyme E1 N subunit; SUMO1 activating enzyme subunit 1; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; UBA2; Ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; UBLE1A
Mass (kDA):
38.45 kDA
Human | |
---|---|
Location: | 19q13.32 |
Sequence: | 19; NC_000019.10 (47130835..47210636) |
Expression level increases during S phase and drops in G2 phase (at protein level).
Nucleus.
PMID: 9920803 by Okuma T., et al. In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2.
PMID: 10217437 by Gong L., et al. Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex.