SACM1L Antibodies

AND SACM1L ELISA kits, SACM1L Proteins

Many biological assays use antibodies to detect SACM1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SACM1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SACM1L antibodies...

We validate the specificity of these antibodies to SACM1L by testing them on tissues known to express SACM1L positively and negatively. Browse below to find the SACM1L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SACM1L Infographic by Boster Bio

All SACM1L Products

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Product

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Specificity

Applications

Price

SACM1L (NM_014016) Human Recombinant Protein

$1062
Cat # PROTQ9NTJ5
20 µg

SACM1L (NM_014016) Human Over-expression Lysate

Human

$628
Cat # LS022908
100 µg

SACM1L Overview

Facts about Phosphatidylinositide phosphatase SAC1.

SACM1L 3D structure. Source: alphafold

Phosphatidylinositide phosphatase SAC1 (SACM1L)

Phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P) (PubMed:24209621). Has low activity towards PtdIns(3,5)P2 (By similarity).

Gene Information

Human
Gene Name:	SACM1L
Uniprot:	Q9NTJ5
Entrez:	22908

Family

Belongs to:

No superfamily

Alternative Names

DKFZp686A0231; EC 3.1.3; EC 3.1.3.36; EC 3.1.3.77; KIAA0851suppressor of actin 1; phosphatidylinositide phosphatase SAC1; SAC1 suppressor of actin mutations 1-like (yeast); SAC1EC 3.1.3.-; Suppressor of actin mutations 1-like protein

Molecular Weight

Mass (kDA):
66.967 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (45689362..45745409)

Tissue Specificity

Detected in heart, brain, lung, liver, kidney, pancreas and testis.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Cholangiocarcinoma
Hyperdiploidy
Major Depressive Disorder
Cell Transformation, Neoplastic
Leukemogenesis
Neoplasms
Leukemia
Depressive Disorder
Dizziness

Acute Lymphocytic Leukemia
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Physiological Sexual Disorders

Interacting Proteins

COPG1

PTMs

Acetylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SACM1L

References

PMID: 11352561 by Kiss H., et al. The LZTFL1 gene is a part of a transcriptional map covering 250 kb within the common eliminated region 1 (C3CER1) in 3p21.3.

PMID: 24209621 by Mesmin B., et al. A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP.