Roundabout homolog 3 Antibodies

AND Robo3 ELISA kits, Roundabout homolog 3 Proteins

Many biological assays use antibodies to detect Roundabout homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Roundabout homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Roundabout homolog 3 antibodies...

We validate the specificity of these antibodies to Roundabout homolog 3 by testing them on tissues known to express Robo3 positively and negatively. Browse below to find the Robo3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Robo3 Infographic by Boster Bio

All Robo3 Products

Product

Figures

Specificity

Applications

Price

Anti-Roundabout homolog 3 ROBO3 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A02990
100ul

Robo3 Overview

Facts about Roundabout homolog 3.

Roundabout homolog 3 (Robo3)

Thought to participate during neural development in axonal navigation in the ventral midline of the neural tube. In spinal chord growth plays a role in guiding commissural axons likely by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1.

Required for hindbrain axon midline crossing (By similarity). .

Gene Information

Mouse
Gene Name:	Robo3
Uniprot:	Q9Z2I4
Entrez:	19649

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

FLJ21044; HGPPS; HGPS; RBIG1horizontal gaze palsy with progressive scoliosis; retinoblastoma inhibiting gene 1; RIG1; ROBO3; roundabout (axon guidance receptor, Drosophila) homolog 3; roundabout homolog 3; roundabout, axon guidance receptor, homolog 3 (Drosophila); Roundabout-like protein 3

Molecular Weight

Mass (kDA):
146.054 kDA

Genomic Context


Mouse

Location:	9\|9 A4
Sequence:	9;

Tissue Specificity

Detected in embryonal spinal chord and hindbrain.

Diseases

Scoliosis, Unspecified
Nervousness
Ocular Motility Disorders
Virus Diseases
Disease Of Adrenal Medulla
Neoplasms
Vesicular Stomatitis
Congenital Neurologic Anomalies
Stomatitis
Innate Immune Response
Melanoma
Hypoplasia

Influenza
Infective Disorder
Rna Virus Infections
Oculomotor Nerve Paralysis
Malignant Neoplasms
Congenital Absence

Pathways

Axon Guidance
Cell Migration
Immune Response
Methylation
Secretion
Innate Immune Response
Viral Replication
Brain Development
Reverse Transcription
Mitosis
Dna Methylation
Cell Death
Gene Silencing

Fertilization
Neurogenesis
Response To Virus
Nuclear Export
Reflex
Cell Fate Specification
Cell Maturation

PTMs

Methylation
Cleavage

Ubiquitination
Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Robo3

References

PMID: 10049565 by Yuan S.S., et al. Cloning and functional studies of a novel gene aberrantly expressed in RB-deficient embryos.

PMID: 15084255 by Sabatier C., et al. The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.