Protein RUFY3 Antibodies

AND RUFY3 ELISA kits, Protein RUFY3 Proteins

Many biological assays use antibodies to detect Protein RUFY3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein RUFY3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein RUFY3 antibodies...

We validate the specificity of these antibodies to Protein RUFY3 by testing them on tissues known to express RUFY3 positively and negatively. Browse below to find the RUFY3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RUFY3 Infographic by Boster Bio

All RUFY3 Products

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Product

Figures

Specificity

Applications

Price

Anti-Protein RUFY3 RUFY3 Antibody

Mouse, Rat

$405
Cat # A09453
100ul

RIPX (RUFY3) (NM_014961) Human Recombinant Protein

$813
Cat # PROTQ7L099
20 µg

RIPX (RUFY3) (NM_014961) Human Over-expression Lysate

Human

$628
Cat # LS022902
100 µg

Anti-RUFY3 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A09453-1
100 µg/vial

RUFY3 Overview

Facts about Protein RUFY3.

RUFY3 3D structure. Source: alphafold

Protein RUFY3 (RUFY3)

Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of one axon by developing neurons (By similarity).

May inhibit the formation of further axons by inhibition of PI3K in small neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321).

Gene Information

Human
Gene Name:	RUFY3
Uniprot:	Q7L099
Entrez:	22902

Family

Belongs to:

No superfamily

Alternative Names

KIAA0871SINGAR1; protein RUFY3; rap2 interacting protein x; Rap2-interacting protein x; RIPX; RUN and FYVE domain containing 3; singar; Singar1; Single axon-regulated protein; single axon-related 1

Molecular Weight

Mass (kDA):
52.965 kDA

Genomic Context


Human

Location:	4q13.3
Sequence:	4; NC_000004.12 (70704204..70808619)

Tissue Specificity

Overexpressed in gastric cancer cells and tissues (at protein level) (PubMed:25766321).

Subcellular Localizations

Cytoplasm. Endomembrane system. Cell projection, invadopodium. Perikaryon. Cell projection. Cell projection, growth cone. Cell projection, filopodium. Cell projection, lamellipodium. Colocalizes with PAK1, F-actin, myosins and integrins in invadopodia at the cell periphery (PubMed:25766321). Colocalized with Ras-related Rab-5 proteins in cytoplasmic vesicles (PubMed:20376209). Accumulates in axon growth cones in a F-actin-dependent manner (By similarity). Colocalized with FSCN1 and F-actin at filipodia and lamellipodia of axonal growth cones (By similarity). Colocalized with DBN1 and F-actin a

Diseases

Inflammation
Atherosclerosis

Pathways

Transport
Intracellular Transport
Translation
Endocytosis
Rna Interference
Secretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RUFY3

References

PMID: 20376209 by Yoshida H., et al. Rab5(Q79L) interacts with the carboxyl terminus of RUFY3.

PMID: 25766321 by Wang G., et al. PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion.