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, No Gclids
40S ribosomal protein S3 Antibodies
AND RPS3 ELISA kits, 40S ribosomal protein S3 Proteins
Many biological assays use antibodies to detect 40S ribosomal protein S3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with 40S ribosomal protein S3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop 40S ribosomal protein S3 antibodies...
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RPS3 Infographic by Boster Bio
All RPS3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M01542
100 μl
Cat # M01542
100 μl
Anti-RPS3 Antibody Picoband®
1 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01542-2
100 μg/vial
Cat # A01542-2
100 μg/vial
RPS3 Overview
Facts about 40S ribosomal protein S3.
40S ribosomal protein S3 (RPS3)
Cleaves phosphodiester bonds of DNAs containing altered foundations with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a frequent DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345).
Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase action of the base excision protein OGG1 (PubMed:15518571).
Gene Information
| Human | |
|---|---|
| Gene Name: | RPS3 |
| Uniprot: | P23396 |
| Entrez: | 6188 |
Family
| Belongs to: |
|---|
| universal ribosomal protein uS3 family |
Alternative Names
40S ribosomal protein S3; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; ribosomal protein S3
Molecular Weight
Mass (kDA):
26.688 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.4 |
| Sequence: | 11; NC_000011.10 (75399491..75422302) |
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus, nucleolus. Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, spindle. In normal cells, located mainly in the cytoplasm with small amounts in the nucleus but translocates to the nucleus in cells undergoing apoptosis (By similarity). Nuclear translocation is induced by DNA damaging agents such as hydrogen peroxide (PubMed:17560175). Accumulates in the mitochondrion in response to increased ROS levels (PubMed:23911537). Localizes to the spindle during mitosis (PubMed:23131551). Localized in cytoplasmic mRNP granules containing untrans
Diseases
- Plant Diseases
- Sterility
- Neoplasms
- Neoplasm Metastasis
- Diarrhea
- Bacterial Infections
- Cold Intolerance
- Inflammation
- Genotoxic Stress
- Escherichia Coli Infections
- Inflammatory Response
- Patient Dependence On
- Innate Immune Response
Interacting Proteins
- IKBKB
- LRRK2
- MDM2
- NEDD8
- NFKB1
- NFKBIA
- PPID
- RELA
- TP53
- YWHAZ
Pathways
- Dna Repair
- Translation
- Methylation
- Localization
- Disease Resistance
- Ribosome Biogenesis
- Secretion
- Cell Death
- Virulence
- Ribosome Assembly
- Cell Cycle
- Rna Processing
- Pathogenesis
PTMs
- Phosphorylation
- Cleavage
- Methylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RPS3
bosterbio.com/bosterbio-gene-info-cards/RPS3
References
PMID: 2129557 by Zhang X.T., et al. Isolation of a cDNA encoding human 40S ribosomal protein s3.
PMID: 1712897 by Pogue-Geile K., et al. Ribosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal protein.