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- Table of Contents
Facts about 60S ribosomal protein L29.
Human | |
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Gene Name: | RPL29 |
Uniprot: | P47914 |
Entrez: | 6159 |
Belongs to: |
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eukaryotic ribosomal protein eL29 family |
60S ribosomal protein L29; Cell surface heparin-binding protein HIP; heparin/heparan sulfate-binding protein; heparin/heparan sulfate-interacting protein; HIPHUMRPL29; HP/HS-interacting protein; MGC88589; ribosomal protein L29
Mass (kDA):
17.752 kDA
Human | |
---|---|
Location: | 3p21.2 |
Sequence: | 3; NC_000003.12 (51993522..51995895, complement) |
Boster Bio sells an antibody against S100A, which is a melanoma-marker. The product can also be used in conjunction a microplate reader, which measures absorbance at approximately 450 nm. It can be dispersed with Boster Pipettes, which can dispense 0.5 ul through 1 ml volumes of aqueous solutions. Multichannel pipettes may be best for you if you intend to work with a lot of samples. If you're thinking about sharing the results from your experiments, you'll appreciate that you can earn credits for the product.
Boster Bio Anti-S100B Monoclonal Antibody can recognize the S100B, also known to be a calcium-binding acidic cell cytoplasmic. In the chemotherapy era, high serum levels of S100B were associated to poor survival. Houghton AN was involved in the study, CordonCardo C and Welt S, Fliegel AB, and Vadhan S.
The protein interacts with several molecules associated with phagocytic functions, including CD44 (merlin), Lamp-1, and Lamp-1. This interaction is consistent and leads to the formation vacuoles. The length of the ezrin fragment that interacts with CD44 was not previously reported. A mutant form of ezrin prevented Lamp-1's recruitment to the plasma membrane.
The antibody was isolated and delivered to mice using a variety of delivery methods. The four-way cellular delivery routes to mice were intradermal. subcutaneous. intramuscularly. Depending upon the antigen used, the protein was delivered intravenously. Similarly, the monoclonal antibody was delivered intravenously, intramuscularly, and intrasplenally.
The MHC and CH3 domains of the antibody's antigen are what make it identifiable. They attract matching helper T cells. This T cell then activates the B cell and produces millions of copies of the antibody. The antibodies then circulate in blood plasma and lymph and attach to the pathogens that express the antigen. These antibodies eventually become a marker for the pathogens that are ready to be destroyed. Antibodies are also capable to neutralize invaders, interfering in receptors, and removing toxic substances.
Boster Bio's Anti-S100B is a monoclonal anti-mouse antibody that binds the S100A protein. It is highly precise, as it only contains one antigenic site per molecule. It is used in diagnostic and research applications because of its high sensitivity and specificity.
The selected myeloma cell lines used to produce the antibody were fused efficiently and allowed for stable, high-level antibody production. These cells are derived from murine myeloma lines and can be obtained from various sources, including the Salk Institute Cell Distribution Center and the American Type Culture Collection. In addition, human and mouse heteromyeloma cell lines have been described by Kozbor, J. and the American Type Culture Collection.
Boster Bio's Anti S100 A Monoclonal Antibody recognises S100A, which is a cancer-related skin protein. It is a member in the S100 protein family. It has two EF-hand calcium binding motifs. The antibody can detect S100A (a cancer-related gene) in a variety tumor types.
Boster Bio's RPL29 markers are derived from one antibody that recognizes the nucleotide sequences of HB/HS interacting proteins. It binds with HB/HS. The RPL29 marker is designed to accurately identify the protein in your samples. This antibody is validated by Western Blotting, Immunohistochemistry, and ELISA techniques.
PMID: 8597591 by Law P.T., et al. A novel cDNA encoding a human homologue of ribosomal protein L29.
PMID: 8662616 by Liu S., et al. cDNA cloning and expression of HIP, a novel cell surface heparan sulfate/heparin-binding protein of human uterine epithelial cells and cell lines.