RNMT Antibodies

AND RNMT ELISA kits, RNMT Proteins

Many biological assays use antibodies to detect RNMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNMT antibodies...

We validate the specificity of these antibodies to RNMT by testing them on tissues known to express RNMT positively and negatively. Browse below to find the RNMT antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNMT Infographic by Boster Bio

All RNMT Products

Product

Figures

Specificity

Applications

Price

Anti-RNMT Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07752
100ul

HCM (RNMT) (NM_003799) Human Recombinant Protein

$1249
Cat # PROTO43148
20 µg

HCM (RNMT) (NM_003799) Human Over-expression Lysate

Human

$628
Cat # LS008731
100 µg

Anti-RNMT Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07752-1
100 µg/vial

RNMT Overview

Facts about mRNA cap guanine-N7 methyltransferase.

RNMT 3D structure. Source: alphafold

mRNA cap guanine-N7 methyltransferase (RNMT)

Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAM/FAM103A1 complicated that methylates the N7 position of the additional guanosine into the 5'-cap structure of mRNAs (PubMed:9790902, PubMed:9705270, PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871). Binds RNA containing 5'-terminal GpppC (PubMed:11114884).

Gene Information

Human
Gene Name:	RNMT
Uniprot:	O43148
Entrez:	8731

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

DKFZp686H1252; EC 2.1.1.56; hcm1p; hCMT1; hCMT1c; hMet; KIAA0398; mRNA (guanine-7-)methyltransferase; mRNA (guanine-N(7)-)-methyltransferase; mRNA cap guanine-N7 methyltransferase; mRNA cap methyltransferase; RG7MT1MET; RNA (guanine-7-) methyltransferase

Molecular Weight

Mass (kDA):
54.844 kDA

Genomic Context


Human

Location:	18p11.21
Sequence:	18; NC_000018.10 (13726645..13764556)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus.

Diseases

Cell Transformation, Neoplastic
Neoplasm Metastasis
Malignant Neoplasms
Metaplastic Cell Transformation
Right-sided Displacement Of Abomasum
Colorectal Cancer

Cytogenetic Abnormality

Interacting Proteins

RAMAC

Pathways

Methylation
Translation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNMT

References

PMID: 9790902 by Tsukamoto T., et al. Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)methyltransferase, an mRNA cap methylase.

PMID: 9705270 by Pillutla R.C., et al. Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.