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- Table of Contents
Facts about Rho-related GTP-binding protein Rho6.
Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments.
Human | |
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Gene Name: | RND1 |
Uniprot: | Q92730 |
Entrez: | 27289 |
Belongs to: |
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small GTPase superfamily |
ARHS; GTP-binding protein; ras homolog gene family, member S; Rho family GTPase 1FLJ42294; RHO6; rho-related GTP-binding protein Rho6; RHOS; Rnd1
Mass (kDA):
26.056 kDA
Human | |
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Location: | 12q13.12 |
Sequence: | 12; NC_000012.12 (48857145..48865870, complement) |
Mostly expressed in brain and liver.
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
PMID: 9531558 by Nobes C.D., et al. A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.
PMID: 11095956 by Aoki J., et al. Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells.