Ribonuclease K6 Antibodies

AND RNASE6 ELISA kits, Ribonuclease K6 Proteins

Many biological assays use antibodies to detect Ribonuclease K6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ribonuclease K6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ribonuclease K6 antibodies...

We validate the specificity of these antibodies to Ribonuclease K6 by testing them on tissues known to express RNASE6 positively and negatively. Browse below to find the RNASE6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: RNF4

RNASE6 Infographic by Boster Bio

All RNASE6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

RNASE6 (NM_005615) Human Over-expression Lysate

Human

$628
Cat # LS006039
100 µg

Anti-RNASE6 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A14127
100 µg/vial

RNASE6 Overview

Facts about Ribonuclease K6.

RNASE6 3D structure. Source: alphafold

Ribonuclease K6 (RNASE6)

Ribonuclease which shows a taste for the pyrimidines uridine and cytosine (PubMed:8836175, PubMed:27013146). Has potent antibacterial activity against a range of Gram-positive and Gram-negative germs, such as P.

aeruginosa, A.baumanii, M.

Gene Information

Human
Gene Name:	RNASE6
Uniprot:	Q93091
Entrez:	6039

Family

Belongs to:

pancreatic ribonuclease family

Alternative Names

EC 3.1.27; EC 3.1.27.-; EC 3.1.27.5; ribonuclease K6; ribonuclease, RNase A family, k6; RNase K6; RNasek6; RNS6

Molecular Weight

Mass (kDA):
17.196 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (20780956..20782467)

Tissue Specificity

Highly expressed in spleen (at protein level) (PubMed:8836175, PubMed:25075772). Has little or no expression in healthy kidneys (at protein level) (PubMed:25075772). Detected in interstitial leukocytes in infected kidneys (at protein level) (PubMed:25075772). Expressed in ureter where it localizes to urothelial and submucosal leukocytes (at protein level) (PubMed:25075772). Strong expression in lung and thymus, and lower expression in heart, placenta, pancreas, liver, brain and skeletal muscle (PubMed:8836175, PubMed:25075772). Also expressed in monocytes and neutrophils (PubMed:8836175).

Subcellular Localizations

Secreted. Lysosome. Cytoplasmic granule.

Diseases

Tumor Angiogenesis
Endometrial Polyp

Pathways

Tissue Remodeling
Proteolysis
Angiogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNASE6

References

PMID: 8836175 by Rosenberg H.F., et al. Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family.

PMID: 25075772 by Becknell B., et al. Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.