RNASE3 Antibodies

AND RNASE3 ELISA kits, RNASE3 Proteins

Many biological assays use antibodies to detect RNASE3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNASE3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNASE3 antibodies...

We validate the specificity of these antibodies to RNASE3 by testing them on tissues known to express RNASE3 positively and negatively. Browse below to find the RNASE3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNASE3 Infographic by Boster Bio

All RNASE3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ECP Antibody

7 Q&As

Human

ELISA, WB

$399
Cat # A03115
100μl

Anti-Ribonuclease 3/RNASE3 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A03115-1
100 μg/vial

Human RNASE3 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP12724
Starting from 10ug

Ribonuclease 3 (RNASE3) (NM_002935) Human Over-expression Lysate

Human

$628
Cat # LS006037
100 µg

RNASE3 Overview

Facts about Eosinophil cationic protein.

RNASE3 3D structure. Source: alphafold

Eosinophil cationic protein (RNASE3)

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a huge selection of biological activities.

Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.

Gene Information

Human
Gene Name:	RNASE3
Uniprot:	P12724
Entrez:	6037

Family

Belongs to:

pancreatic ribonuclease family

Alternative Names

eosinophil cationic protein; ECP; ribonuclease, RNase A family, 3; RNS3

Molecular Weight

Mass (kDA):
18.385 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (20891403..20892348)

Subcellular Localizations

Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.

Diseases

Asthma
Inflammation
Eosinophilia
Rhinorrhea
Allergic Rhinitis (disorder)
Allergy
Hay Fever
Dermatitis, Atopic
Dermatitis
Rhinitis, Allergic, Perennial
Allergic Asthma
Bronchial Hyperreactivity
Polyps

Infective Disorder
Food Allergy
Nasal Polyps
Pneumonia
Plant Diseases
Welts
Allergic Conjunctivitis

Pathways

Eosinophil Activation
Pathogenesis
Secretion
Hypersensitivity
Sensitization
Immune Response
Inflammatory Response
Cytokine Production
Tissue Remodeling
Cell Growth
Cytolysis
Gene Silencing
Platelet Activation

Protein Secretion
Endocytosis
Neutrophil Activation
Reflex
Flight
Cell Death
Eosinophil Degranulation

PTMs

Cleavage

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNASE3

References

PMID: 2473157 by Rosenberg H.F., et al. Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity.

PMID: 2387583 by Hamann K.J., et al. Structure and chromosome localization of the human eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily.